Two Neural Circuits Control Muscle Autophagy via Calcium and TGF-β Signaling
Understanding how the nervous system remotely governs cellular housekeeping in distant tissues could reshape how we think about age-related muscle wasting and…
Found 1276 results for "longevity"
Understanding how the nervous system remotely governs cellular housekeeping in distant tissues could reshape how we think about age-related muscle wasting and…
A largely overlooked fact about copper is that at supraphysiological concentrations it doesn't merely impair cells — it hijacks their own metabolic machinery…
For anyone serious about understanding their biological age rather than their calendar age, the gap between cutting-edge epigenetic research and accessible…
The pharmaceutical industry's most stubborn problem is not scientific ignorance — it is the fundamental mismatch between the animal models used to predict…
For adults navigating family planning timelines, the biology of reproductive aging rarely matches the social narrative of fertility being easily extended into…
A sweeping metabolomics atlas spanning 2,271 samples across multiple tissues from two AD transgenic mouse models (3xTg and 5xFAD) — run under both colonized…
Two iridoid compounds isolated from Rhododendron pachypodum flowers — compound 5 (a newly characterized analogue) and compound 8 (a known iridoid) — extended…
For anyone practicing intermittent fasting, the assumption has been that eating within a compressed daily window benefits everyone equally. A rigorous…
For decades, the ovary after menopause was considered a spent organ—biologically silent once its follicles were gone. New molecular evidence overturns that…
Chronic psychological stress impairs hematopoietic stem cell (HSC) self-renewal and lymphoid differentiation by suppressing neuronal activity in the medial…
The PROMETHEUS feasibility trial enrolls 20 middle-aged-to-older adults in an 8-week multimodal intervention stratified by individual 'gerotypes' — biological…
Every anti-aging intervention trial faces the same problem: how do you measure whether a treatment is actually slowing immune aging before waiting decades for…
Understanding why humans live decades while fruit flies live weeks has challenged biologists for generations. A new mechanistic framework now offers a…
For decades, exercise has been championed as the closest thing to an anti-aging intervention available to healthy adults. But a granular molecular analysis…
For the roughly 50 million people worldwide living with Alzheimer's, Parkinson's, Huntington's disease, or ALS, approved treatments manage symptoms but leave…
High acylglycerol kinase (AGK) expression in glioblastoma correlates with poor prognosis in TCGA patient data. Paradoxically, AGK knockdown inhibits tumor…
For anyone tracking biological age as a modifiable health marker, this finding reframes a fundamental assumption: epigenetic aging may not be a slow…
A massive treatment gap exists between who qualifies for today's most transformative metabolic medicines and who actually receives them — and a new…
For the roughly 100,000 Americans living with pulmonary fibrosis, knowing whether a genetic mutation drives the disease isn't just academic—it reshapes…
The senolytic combination of dasatinib and quercetin (D+Q) administered long-term to naturally aged mice reduced senescence biomarkers p16, p21, and SA-β-gal…