Found 935 results for "longevity"
Immune deterioration with age has long been attributed partly to the shrinking thymus, but pinning down a druggable molecular target within the gland's structu…
One of the most persistent puzzles in aging biology is explaining why the immune system shifts from a protective force into a driver of chronic, low-grade infl…
For the roughly 160,000 people diagnosed with multiple myeloma each year worldwide, the standard expectation has been indefinite drug therapy — a regimen that…
The compatibility between an organism's mitochondrial and nuclear genomes may be a surprisingly powerful determinant of how quickly cells age — a finding with…
How memory actually forms at the cellular level remains one of neuroscience's most consequential open questions — and the answer has implications for understan…
The idea of using living organisms as precision cancer-fighting agents is no longer science fiction — it is becoming an increasingly sophisticated engineering…
Most adults undergo an ECG at some point in their lives, yet the standard interpretation extracts only a fraction of the physiological information embedded in…
The conventional view of skeletal muscle as a passive tissue involved mainly in movement and metabolism is increasingly giving way to a more dynamic picture: m…
Cardiac hypertrophy — the pathological thickening of heart muscle — remains one of the leading precursors to heart failure, yet its molecular triggers are inco…
How cancer cells manage their molecular communications under duress has long been a blind spot in tumor biology — and closing that gap could reshape therapeuti…
Cognitive test scores across entire populations have been declining in several wealthy nations after decades of gains — but treating this as a uniform trend ma…
Diarrhoeal and enteric infections remain a leading killer of young children globally, yet the pace of improvement has measurably slowed — a warning signal for…
The accumulating burden of senescent cells in the aging brain may represent one of the most actionable upstream targets yet identified for neurodegenerative di…
A new mechanistic framework resolves a long-standing paradox in polyamine biology: spermidine drives autophagy by inhibiting EP300 acetyltransferase and activa…
A near-comprehensive national dataset revealing that substance use disorders carry a dramatically elevated mortality burden should prompt any health-conscious…
The long-standing assumption that women face worse Alzheimer's disease outcomes simply because they live longer may be fundamentally incomplete. Emerging evide…
Malabsorption disorders often evade early detection, and exocrine pancreatic insufficiency (EPI) is among the most commonly missed culprits behind chronic dige…
The dominant assumption in longevity research has long been that aging is either something that happens to cells from within, or something imposed on them by t…
For decades, the quest for a drug that measurably slows biological aging has remained elusive. Evidence from a rigorously controlled trial now suggests that se…
Uveal melanoma — the most common primary eye tumor in adults — has long been an orphan of oncology, with metastatic disease carrying a median survival under 12…