LSD at Nanomolar Doses Extends Worm Lifespan 17.6% via Serotonin Receptors
Chronic exposure to nanomolar lysergic acid diethylamide extended lifespan in the roundworm Caenorhabditis elegans by up to 17.6% at the 25% survival point…
Found 1276 results for "longevity"
Chronic exposure to nanomolar lysergic acid diethylamide extended lifespan in the roundworm Caenorhabditis elegans by up to 17.6% at the 25% survival point…
In male C57BL/6N mice fed a fast-food diet for 15 weeks, then dosed daily for 9 more weeks with an Angelica keiskei extract enriched in the chalcone…
Whether the weight loss seen in tightly controlled GLP-1 trials survives contact with everyday life is one of the most practical questions for adults…
Among 209 naturally cycling women without diabetes (mean age 43, BMI 24.3) wearing continuous glucose monitors for up to 14 days, average glucose and glucose…
In fruit flies subjected to repetitive mild traumatic brain injury, two intermittent fasting regimens produced longer lifespans, lower mortality and better…
In the prospective Lifelines cohort tracking 105,812 Dutch adults over a median 13.25 years, adherence to the MEDLIFE index — a 23-item composite scoring…
A Bayesian network meta-analysis of 43 randomized controlled trials (2,433 participants) systematically compared lifestyle interventions for cardiometabolic…
Among 10,462 UK Biobank participants who later developed cancer, higher cardiorespiratory fitness (CRF) at baseline was associated with dramatically lower…
In the Mexico City Prospective Study — 144,900 adults followed for up to 24 years — higher circulating omega-3 fatty acids were consistently linked to lower…
In a controlled cross-sectional cohort of 80 intact Beagles aged 1–11 years, immune aging proved heterogeneous and non-linear: absolute leukocyte counts…
In aged mice, bone formation declines in tandem with a measurable impairment of glycolysis within bone tissue itself. Using in vivo stable-isotope tracing…
In a controlled cross-sectional cohort of 80 intact Beagles aged 1–11 years, immune aging proved heterogeneous and non-linear: absolute leukocyte counts…
Among 6,690 adults in the CHRIS cohort study, higher adherence to five established healthy dietary patterns — including the Mediterranean diet, Alternate…
In a secondary analysis of the SPARX Phase 2 randomized clinical trial (128 de novo Parkinson's disease patients), sedentary time significantly modified…
In 892 older Singaporean adults tracked across 32 years (1993–2025), higher adherence to the DASH diet during midlife (ages 44–55) and early elderhood (ages…
Direct activation of AMP-activated protein kinase (AMPK) using compound 991 — a small molecule that binds AMPK allosterically, bypassing the indirect…
In Drosophila, genetic ablation of Lsp2 — a protein previously classified only as a larval storage protein but now identified as an adipose-tissue effector…
A specific probiotic strain, Bifidobacterium pseudocatenulatum CL256B, converts the poorly absorbed citrus flavanone hesperidin into its bioactive form…
A pre-registered systematic review and network meta-analysis of 227 randomised controlled trials compared exercise-only programmes against exercise combined…
Pooling randomized controlled trials comparing ketogenic (KD) and Mediterranean diets (MD) head-to-head in adults, this meta-analysis found KD produced…