Breaking results from peer-reviewed journals, clinical trials, and medical research.. Browse synthesized summaries from peer-reviewed journals and trusted health sources.
Pharmacovigilance data show semaglutide with a reporting odds ratio of 120.8 (95% CI 110.6–132.0) for non-arteritic…
Engineers modified Saccharomyces cerevisiae to produce pro-DALAP, a precursor of a dual GLP-1/GIP receptor agonist…
Pooling seven trials and just 110 patients on SGLT2 inhibitors, this single-arm meta-analysis found significant…
Circulating taurine rises with age in humans and mice, contradicting the popular idea that falling taurine drives…
In 618 MASLD patients following 48 weeks of guideline-based lifestyle management, metabolic-cluster subtypes…
Pooling three cohorts, patients who took an SGLT2 inhibitor during or after acute kidney injury had 35% lower…
In mice given eight azoxymethane injections over 28 weeks, a 7.5% refined inulin diet produced colon tumors in roughly…
Pooling five randomized trials, one Mendelian randomization study and thirteen conventional multivariable regression…
Whole-genome sequencing of 520 esophageal and gastroesophageal junction adenocarcinomas from eight countries found…
Chronic exposure to nanomolar lysergic acid diethylamide extended lifespan in the roundworm Caenorhabditis elegans by…
A systematic review of observational studies and cohort analyses finds that higher nut consumption, and especially…
In a secondary analysis of a randomized trial of 266 low-income adults with early-to-moderate chronic kidney disease…
Among 1,558 postmenopausal women with non-metastatic breast cancer (mean age 71) from the Cancer Prevention Study-II…
In 892 patients who underwent laparoscopic sleeve gastrectomy at one Israeli tertiary center (2009-2022), 262 Arab and…
A pre-registered PRISMA/SWiM synthesis of 248 studies (100 RCTs, 62 cohorts) in adults 60 and older found the most…
Pooled data show that higher apnea-hypopnea index (AHI) tracks with lower DTI-ALPS values, an MRI proxy for glymphatic…
Among 2,806 CARDIA participants followed from roughly age 25 to 60, those who combined a high-quality DASH-style diet…
Among 3,268 US adults aged 40 and older with ankle-brachial index testing (NHANES 1999-2004, 235 with peripheral…
Across 222,109 adults who underwent diagnostic sleep testing in Kaiser Permanente Southern California, apnea-hypopnea…
Among 7,113 US adults with chronic kidney disease in NHANES (2005-2018), those in the highest quartile of the dietary…
Across 247,316 continuous glucose monitoring days from 716 Apple Women's Health Study participants, women with…
Adding linafexor, a pulsatile oral FXR agonist (4 mg daily), to low-dose semaglutide (0.5 mg weekly) produced 6.17%…
Pooling HCHS/SOL, MESA and ARIC (N=11,563), long sleep (9+ hours) tracked with lower baseline global cognitive…
In the 14-year ARMMS-T2D follow-up of 262 adults with type 2 diabetes (mean BMI 36.4, HbA1c 8.5%), 58% randomized to…
Across eight randomised trials (1,204 participants with chronic kidney disease stages 3a-5), dietitian-delivered…
In the All of Us Research Program, women had higher median LDL-C than men across most age strata, with the gap widest…
In rats fed a high-fat, high-cholesterol diet, two Lactiplantibacillus plantarum strains, LP5 and BX62, given alone or…
Among 224,510 new SGLT2 inhibitor users and 698,012 new DPP-4 inhibitor users with type 2 diabetes in Taiwan's…
Loneliness and social isolation are often framed as drivers of rapid aging, but this analysis suggests the story is…
Hearing loss affects a majority of adults over 70, yet it is often dismissed as a nuisance of aging rather than a…
Among 400 primary prevention patients in a community cardiology practice, coronary artery calcium (CAC) score tracked…
In a placebo-controlled trial of older adults with reduced muscle strength, 12 weeks of heat-treated…
Across 78 randomized trials (8,452 adults with metabolic syndrome and overweight or obesity), every structured…
In 81 healthy men aged 18 to 80, free testosterone fell with age, as did muscle mass and leg press strength. Yet…
Adults with moderate-to-severe knee osteoarthritis had weaker knee extensors, poorer muscle quality, and more…
In a double-blind crossover trial of 23 adults with overweight or obesity (mean BMI 36.4) and mild…
In obese mice, 8 weeks of treadmill running (300 min/week) and the ACE inhibitor enalapril (10 mg/kg/day) each cut…
Across 466,864 UK Biobank participants followed a median 13.8 years, Fried-phenotype frailty was linked to higher risk…
Across 136,781 US adults with confirmed type 2 diabetes in linked health records, remission (two HbA1c readings below…
A 36-week community multicomponent exercise programme (the Vivifrail model, combining strength, balance, gait and…
In 50 male C57BL/6 mice fed a high-fat, high-fructose diet for 12 weeks, early renal damage appeared: more vascular…
In a propensity-matched TriNetX cohort of 218,043 adults with serious mental illness, type 2 diabetes, obesity, and…
In a post hoc analysis of the CAUGHT-CAD randomized trial, 338 asymptomatic, statin-naive, intermediate-risk adults…
A meta-analysis of seven clinical studies found curcumin supplementation lowered serum aminotransferases in people…
Pooling three independent Japanese cohorts (five analytic estimates per outcome), adherence to predefined…
Among 2,049,641 Korean health-checkup participants, fatty liver (Fatty Liver Index ≥30) raised all-cause mortality in…
Sixty-one older men (BMI ≥ 23) completed 28 days of alternate-day fasting, randomized to calorie-matched supplements…
Whether the weight loss seen in tightly controlled GLP-1 trials survives contact with everyday life is one of the most…
Among Health and Retirement Study participants aged 65 and older who had been persistently inactive and were free of…
In the Framingham Offspring cohort (2,308 adults, mean age 61.5; 1,148 dementia-free adults aged 60+ followed 10…
Among 269,617 Medicare-age adults starting first-line hypertension treatment, those who began an angiotensin receptor…
In fruit flies subjected to repetitive mild traumatic brain injury, two intermittent fasting regimens produced longer…
Among 209 naturally cycling women without diabetes (mean age 43, BMI 24.3) wearing continuous glucose monitors for up…
A scoping review screened 803 records and kept 12 studies (8 randomised trials, 3 cohorts, 1 open-label trial) testing…
Across 26,909 Korean adults in the 2014-2021 national nutrition survey, 23.2% had metabolic dysfunction-associated…
An umbrella review of 22 meta-analyses, covering 69 unique primary studies and 286,584 adults, found that calcium…
Across 6,214,569 disease-free Korean adults followed from 2006-2009 through 2022, alcohol intake rose with risk for…
Pooling 20 randomized trials, traditional Chinese mind-body training (tai chi, qigong and related practices) raised…
A single 200 μmol/kg nitrate dose from beetroot juice left rate of torque development unchanged versus a nitrate-free…
Among 200 Ghanaians aged 60 and over (mean 69.8 years), dietary inadequacy was widespread: more than half fell short…
Among 7,135 insured, symptom-free Florida adults aged 45 to 70 with at least one cardiovascular risk factor, coronary…
Pooling 16 public RNA-seq datasets (364 healthy men aged 18-92), a new R pipeline called MetAR found androgen receptor…
Across 2,051,275 eligible adults aged 55–80 in the TriNetX network, starting an angiotensin receptor blocker (ARB)…
In mice given dexamethasone (20 mg/kg for 12 days) to induce muscle wasting, a 4-week ladder-climbing resistance…
Among 174,718 UK Biobank adults followed a median 14.6 years, those with high early-life risk (low birth weight…
A systematic review of PubMed, Embase, and Cochrane records through January 2026 found only three eligible studies…
In a cross-sectional analysis of 44,982 adults (with a 1,426-person matched MRI subsample), each standard-deviation…
Among 4,016 Australian primary care patients starting statins for primary prevention, 3.5% met an electronic-record…
Among 57,611 UK Biobank participants followed a median 5.1 years, people with type 2 diabetes and high systolic blood…
In a retrospective cohort of 4,269 adults in a telemedicine obesity program, those receiving individualized…
Across four harmonized aging cohorts spanning Asia, North America and Europe, adults at age 50 who did both structured…
Across 34 studies and 15,656 adults with type 2 diabetes, patients consistently ranked glycaemic efficacy…
Among 4,397 women in the NYU Women's Health Study (mean age 46 at baseline, 79 at follow-up), those in the top tertile…
Among 3,966 patients with confirmed primary aldosteronism (PA) in a 14,750-patient hypertensive cohort, the share…
Pooling 14 placebo-controlled trials (76,969 adults with type 2 diabetes), SGLT2 inhibitors lowered the composite of…
Among 1,124 U.S. adults aged 40-59 from NHANES (508 for development, 616 for temporal validation), adding DXA body fat…
Among 396 community-dwelling Taiwanese adults (mean age 65, mean serum 25(OH)D 28.3 ng/mL, mean gait speed 0.91 m/s)…
Across three cohorts totaling 12,042 patients with chronic kidney disease, higher resting heart rate (RHR) predicted…
In a 12-month unpredictable chronic mild stress model in mice, chronic stress amplified systemic inflammation, damaged…
Across 56,754 adults with type 2 diabetes in Teladoc's remote monitoring program (2021-2025), estimated A1c from…