Found 1276 results for "longevity"
The idea that Parkinson's disease begins in the gut has gained substantial traction over the past decade, but pinpointing which microbial signals are most…
Over a million children still die each year from diseases that are largely preventable with clean water, sanitation, and vaccines — yet the pace of…
A microbiome aging clock (MicroAge) built from enterotype-specific gut microbial shifts across multiple Chinese cohorts identified Bifidobacterium…
A foundational assumption in longevity research — that suppressing the cGAS–STING inflammatory pathway would extend healthy lifespan — has just been upended…
A pan-European survey across 24 sleep centres in 14 countries reveals that tirzepatide and other GLP-1 receptor agonists are rapidly entering sleep medicine…
Ubiquitous degradation of the DAF-2/IGF-1 receptor in male Caenorhabditis elegans extends median lifespan by over 440% — among the largest single-intervention…
Inherited cholesterol disorders remain one of the most underdiagnosed cardiovascular risk conditions in clinical practice, affecting roughly 1 in 250 people…
Overall cardiac mortality has fallen dramatically in the United States over recent decades, yet that headline improvement obscures a troubling shift in the…
What if chronic fatigue, anxiety, and accelerated aging share a common biological root — not in the brain itself, but in a signaling molecule released when…
Chronic low-grade inflammation — now widely termed inflammaging — is increasingly recognized as a central driver of functional decline and age-related…
Chronic psychological stress has long been suspected to accelerate biological aging, but the molecular machinery connecting them has remained elusive. A newly…
The assumption that aging unfolds similarly in men and women has quietly shaped decades of longevity research — and it may be fundamentally wrong. New…
For the roughly 7% of the population carrying at least one APOE ε2 allele, this report offers a striking window into what extreme aging can look like when the…
Approximately 10% of participants in controlled obesity trials fail to achieve even 5% total body weight loss on GLP-1 or dual GLP-1/GIP receptor agonists…
The cyclin-dependent kinase inhibitor p21 (CDKN1A) behaves in fundamentally opposing ways across exercise contexts in the aging brain. Sustained physiological…
Obesity doesn't just add weight — it fundamentally rewires the immune system in ways that linger even after weight loss, leaving the innate immune defenses…
Dioscin, a steroidal saponin derived from medicinal herbs, extends lifespan in C. elegans and reduces senescence markers in naturally aged C57BL/6J mice…
Most immunology research focuses on eliminating pathogens, but a quieter survival strategy — disease tolerance — may be equally vital. New findings published…
The promise of epigenetic clocks has always been tantalizing: a molecular readout of how fast you're actually aging, responsive enough to detect whether an…
Depression research has long been hampered by a fundamental gap: the molecular machinery inside the living human hippocampus has been nearly impossible to…