Found 1276 results for "longevity"
Blood stem cells carrying faulty p53 genes may exploit the body's inflammatory responses to gain an unfair survival advantage, potentially explaining why…
Two compounds increasingly popular among longevity enthusiasts may work through fundamentally different cellular pathways, suggesting strategic timing and…
The trajectory of human cardiovascular health reveals a sobering paradox: despite decades of medical advances and prevention campaigns, the global burden of…
The silent epidemic of gout is reshaping global health patterns, with 57 million people now living with this painful joint condition that disproportionately…
The relationship between metabolic rate and body size may be far more complex than previously understood, with profound implications for how we interpret…
The most metabolically resilient animals on Earth may hold keys to solving humanity's most stubborn health challenges. From bears that emerge from months-long…
Understanding how immune cells maintain tissue health could unlock new approaches to inflammatory diseases and age-related tissue dysfunction. Macrophages…
High glucose levels accelerate bone marrow mesenchymal stem cell senescence through a newly identified Mettl3/Foxo3/Sirt1 molecular axis. In diabetic mice…
Daily resveratrol supplementation at 500mg for 18 weeks significantly improved balance, gait speed, and knee range of motion in 129 osteoarthritis patients…
Aspartame at 100 μM concentrations activated autophagy genes (bec-1, unc-51, lgg-1, lgg-2, atg-5) in C. elegans worms, extending lifespan while enhancing…
Eleutheroside B, a compound from Siberian ginseng, dramatically reduced amyloid-beta and tau protein accumulation while improving cognition and lifespan in…
Lin's research reveals a sophisticated glucose-sensing mechanism where the AXIN:LKB1 complex translocates to lysosomal surfaces when aldolase detects low…
The explosive rise in ultra-processed food consumption across Europe represents a fundamental shift in cancer risk that most adults underestimate. These…
The mystery of why kidney disease accelerates heart failure may finally have a molecular explanation. While cardiovascular complications kill more than half…
Reduced forms of NAD+ precursors—NMNH and NRH—triggered dramatically broader metabolic and transcriptional changes in mouse liver cells compared to their…
One month of rapamycin treatment in reproductively aged 10-month-old female mice suppressed mTOR signaling and reduced cellular senescence, inflammation…
Pathogenic gut bacteria and their metabolites accelerate telomere shortening through oxidative stress pathways, while shortened telomeres compromise gut…
The pursuit of longevity through dietary intervention may have found a previously overlooked molecular pathway that operates independently of the well-studied…
The world's most vulnerable populations remain trapped in cycles of malnutrition despite nearly a decade of coordinated global health initiatives. This…
Just 14 days of head-down tilt bedrest in adults aged 55-65 significantly decreased beneficial gut bacteria including Akkermansia and Lactobacillus while…