Found 1201 results for "longevity"
Dioscin, a steroidal saponin derived from medicinal herbs, extends lifespan in C. elegans and reduces senescence markers in naturally aged C57BL/6J mice…
Most immunology research focuses on eliminating pathogens, but a quieter survival strategy — disease tolerance — may be equally vital. New findings published…
The promise of epigenetic clocks has always been tantalizing: a molecular readout of how fast you're actually aging, responsive enough to detect whether an…
Depression research has long been hampered by a fundamental gap: the molecular machinery inside the living human hippocampus has been nearly impossible to…
Identifying reliable tissue-level markers of biological aging has long been a bottleneck for both clinical assessment and longevity research. A structural…
For anyone banking on epigenetic clocks to guide longevity interventions, this investigation lands as a serious reality check. The question it answers is…
Pooling data from 11 Indian studies covering 3,512 children and adolescents under 18, this meta-analysis estimates an overall NAFLD prevalence of 35.4% (95%…
Analyzing weekly all-cause mortality data from 31 European countries (2015 onward, COVID-19 period excluded from baseline), NeMMo — an evolution of the…
Applying directed evolution to the Drosophila gut microbiome outside the host generated a paraquat-resistant (PQR) microbial community that, when transplanted…
Treating 12-month-old female mice carrying the APOE4 Alzheimer's risk allele with 14.4ppm 17α-estradiol (17αE2) for six months reduced adiposity and improved…
For decades, adipose tissue was dismissed as passive energy storage, but mounting evidence positions it as a master regulator of systemic aging. A newly…
One of the most vexing problems in longevity medicine is that the same cellular arrest mechanism that protects against cancer — senescence — also generates a…
One in eight people worldwide now lives with a diagnosable mental disorder, and the cumulative toll on healthy years of life has grown substantially over…
Psoriasis patients (n=20) showed significantly accelerated epigenetic aging compared to matched controls across four mortality-predictive DNA methylation…
Understanding how cells shuttle glycerol across their membranes may matter far more than it first appears. Glycerol is not merely a byproduct of fat breakdown…
For decades, the cancer vaccine field carried a reputation for overpromising and underdelivering — Sipuleucel-T's 2010 approval stood as both a milestone and…
A diabetes drug taken by hundreds of millions of people worldwide may be quietly doing something far more profound than regulating blood sugar — and the…
For the millions of adults managing knee osteoarthritis, intra-articular corticosteroid injections have become a go-to bridge between failed oral pain relief…
Blood cancers driven by clonal stem cell mutations occupy a unique space in oncology — they evolve slowly, often over decades, yet carry serious risks of…
Every time a cell's DNA suffers a double-strand break — one of the most catastrophic forms of genetic damage — it must orchestrate a precise molecular repair…