Longevity
4 Skin Microbes Predict Age Group with 0.97 AUC Accuracy
A pilot study of 80 healthy Chinese participants across four age cohorts (centered at 10, 30, 50, and 70 years) mapped bacterial and fungal communities on…
Search Results: "longevity"
Found 1276 results for "longevity"
⚕️ Synthesized briefings — original sources linked for full context.
Supplements
Spermidine Restores RANKL/OPG Balance, Cuts Bone Loss in Steroid Osteoporosis
At 20 mg/kg co-administered with dexamethasone (7 mg/kg IM weekly for 5 weeks) in a rat model, spermidine reversed key markers of glucocorticoid-induced…
Longevity
Review Maps Senolytics Like Dasatinib+Quercetin Against Ovarian SASP Pathways in Preclinical Models
Ovarian aging accelerates through cellular senescence cascades: primordial follicle depletion, SASP-driven stromal inflammation, mitochondrial dysfunction…
Supplements
Daily Probiotics Slow Telomere Shortening in Adults Over 60 in RCT
In a randomized, double-blind, placebo-controlled substudy of the PROBIOSENIOR trial, 46 adults aged 60+ received either SYNBIO® probiotics at 5×10⁹ CFU daily…
Nutrition
54 Cohorts, 1.8M People: Each Mediterranean Diet Point Cuts Death Risk 4%
Pooling 54 prospective and retrospective cohort studies encompassing 1,833,267 participants and 346,034 deaths, this meta-analysis quantifies Mediterranean…
Studies
Autonomous AI Agents Accelerate Drug Discovery Across Six Critical Pipeline Stages
Every decade or so, a technological shift compresses pharmaceutical timelines that once spanned fifteen years into something far shorter. The emergence of…
Studies
Mitochondrial Copper Transporter SLC25A3 Guards Against Fatal Cell Death Pathway
Copper is one of biology's most paradoxical minerals — essential in trace amounts yet lethal when it accumulates in the wrong cellular compartment. A…
Studies
Multi-Cause Death Certificate Analysis Reveals Hidden Mortality Burden in US Data
How Americans actually die is more complex than official death statistics suggest — and that gap between recorded data and biological reality has major…
Studies
Stronger Innate Immune Responsiveness Predicts Worse Flu Symptoms in Challenge Study
Most people assume a more reactive immune system is unconditionally protective — this research challenges that intuition in a clinically precise way, with…
Longevity
Ergothioneine Mediates 31.5% of Antacid-Linked Cognitive Decline Risk
Screening 991 blood metabolites against cognitive performance and brain MRI markers in 1,082 dementia-free middle-aged participants (Rotterdam Study), this…
Studies
Fish-Specific Oxygen Sensor Activates Immunity Via Novel Non-Enzymatic Mechanism
Understanding how oxygen levels regulate immune responses could reshape how scientists approach inflammatory diseases and hypoxia-related conditions in humans…
Longevity
p53 Cell-Cycle Genes Gtse1 and Cdkn1a Are Critical Effectors in Mouse Model of Constitutive p53 Activation
Understanding what actually executes p53's tumor-suppressing and aging-related commands inside living organisms—not just in cell cultures—has been one of…
Longevity
Arterial Stiffness Linked to Three Alzheimer's Biomarkers in Black Older Adults
For a population carrying a disproportionate Alzheimer's burden, identifying early, measurable warning signs before cognitive decline appears is one of…
Studies
Beyond Blood Thinners: Next-Generation Anticoagulants Target Bleeding-Free Clot Prevention
For the millions of adults managing atrial fibrillation, deep vein thrombosis, or cardiovascular risk, the promise of stopping dangerous clots without…
Longevity
Short Telomeres Predict 30% Higher 10-Year Death Risk in Hospitalized Elderly
Among 872 hospitalized adults aged ≥65 in Italy's Report-AGE cohort, shorter-than-expected leukocyte telomere length — expressed as age-adjusted residuals…
Longevity
25-Year Bibliometric Maps Redox-Mitochondrial Mechanisms Behind Exercise-Telomere Protection
A bibliometric analysis of 858 telomere-exercise publications from 2000–2025 documents a field-wide mechanistic pivot: the research landscape shifted from…
Longevity
Rapamycin Attenuates Age-Related Changes in Marmoset Salivary Glands
In aging common marmosets (Callithrix jacchus), submandibular glands exhibit a striking degenerative profile: loss of mucous and serous acinar units, ductal…
Studies
Lower Respiratory Infections Still Kill Millions Despite Three Decades of Progress
Lower respiratory infections remain one of the most persistent threats to human survival despite decades of vaccines, antibiotics, and public health campaigns…
Longevity
Myc Protein Rescues Mitochondrial Defects Tied to Childhood Progeria Disorder
For the millions of families navigating rare accelerated-aging disorders in children, identifying molecular rescue pathways offers a rare window of hope. New…
Supplements
Resveratrol Isomers Show Opposite Effects on Mitochondrial Enzyme Linked to Neurodegeneration
For anyone taking resveratrol as a longevity supplement, the molecular form in their capsule may matter far more than the dose — and a new mechanistic…