A novel computational tool analyzed 2,778 American adults and found average daily polyphenol consumption of 517mg per 1,000 calories, with coffee, green tea, and black tea serving as primary sources alongside apples, wine, and berries. The tool identified specific compounds like cryptochlorogenic acid and neochlorogenic acid as top contributors, while calculating that typical American diets have pro-inflammatory potential based on polyphenol profiles. This automated mapping represents a significant methodological advance for nutrition research. Polyphenols have emerged as critical bioactive compounds linked to cardiovascular health, cognitive function, and longevity through anti-inflammatory and antioxidant mechanisms. The ability to precisely quantify polyphenol intake from complex dietary data addresses a major research bottleneck that has limited population-level studies. However, the findings reveal concerning dietary patterns, as the calculated inflammatory index suggests most Americans consume insufficient anti-inflammatory polyphenols relative to pro-inflammatory foods. While this preprint awaiting peer review offers promising analytical capabilities, the health implications depend on translating these intake estimates into clinical outcomes. The tool's 97% food mapping success rate suggests reliable data, though validation against biomarkers would strengthen confidence in these polyphenol estimates.