Found 1276 results for "longevity"
A single molecular target that, when silenced, simultaneously prevents cognitive decline, muscle wasting, heart dysfunction, and systemic inflammation—that is…
Understanding how neurons maintain mitochondrial health across decades of high metabolic demand may be one of the most consequential questions in longevity…
The idea that your morning coffee might do more than sharpen focus has gained a molecular foothold. Understanding precisely how caffeine interacts with aging…
Eating window duration follows a U-shaped mortality curve — a counterintuitive finding that challenges the blanket enthusiasm for aggressive time-restricted…
Food-derived bioactive peptides from plant, animal, and marine sources can extend healthspan and lifespan in model systems by modulating three conserved…
Bioinformatics analysis of GEO datasets identified 808 differentially expressed genes in osteoarthritis (OA), with neutrophil extracellular trap (NET)…
When artificial intelligence fails in clinical medicine, the culprit is often a mismatch between the curated datasets used for training and the messy…
A Mayo Clinic team proposes a formal classification system called 'senotypes' to organize the profound heterogeneity of senescent cells across five…
Intracellular complement proteins C3 (intC3) and C5 (intC5) — components of what is now termed the 'complosome' — engage in extensive crosstalk with mTOR…
The global shortfall of dementia specialists represents one of the most urgent bottlenecks in neurodegenerative care — millions of patients wait months or…
For decades, chronic low-grade inflammation in older adults was treated as a background condition — an inevitable consequence of aging with modest clinical…
Liver disease rarely announces itself early — by the time metabolic dysfunction-associated steatotic liver disease (MASLD) is clinically apparent, significant…
Precise control over how cells destroy their own proteins sits at the heart of aging, neurodegeneration, and cancer biology. When the proteasome — the cell's…
For decades, the textbook model of G-protein-coupled receptor (GPCR) signaling placed all meaningful activity at the plasma membrane — a tidy picture that…
Salt stress is one of agriculture's most devastating crop threats, and understanding the molecular machinery that helps staple crops survive it has direct…
The field of cellular senescence has long wrestled with a fundamental problem: not all senescent cells are equal, yet researchers have been treating them as…
Precision medicine for aging has long promised individualized interventions but rarely delivered them in a rigorous, multi-modal format. The PROMETHEUS trial…
Dangerously elevated blood potassium is one of the few electrolyte emergencies that can kill within minutes, yet the drugs used to treat it carry their own…
As climate-driven disasters intensify, understanding who bears the heaviest psychological burden — and why — is no longer an academic question. The January…
Cognitive decline has long been attributed to aging, genetics, and cardiovascular risk — but mounting evidence implicates kidney dysfunction as an…