RARβ Agonist KCL-286 Cuts Neuronal DNA Breaks and Brain Inflammation in Alzheimer's Mice
One of the most frustrating gaps in Alzheimer's therapeutics is the lack of agents that address the disease's earliest molecular insults rather than its downst…
Found 1467 results for "cancer"
One of the most frustrating gaps in Alzheimer's therapeutics is the lack of agents that address the disease's earliest molecular insults rather than its downst…
Pancreatic ductal adenocarcinoma remains one of the deadliest cancers, with five-year survival rates below 12% and limited chemotherapy efficacy. Emerging evid…
One of the most stubborn challenges in oncology is that tumors engineer their own survival environment — starving themselves of oxygen while simultaneously rew…
One of the central ambitions in cancer immunotherapy is sustaining the killing power of CD8+ T cells long enough to defeat tumors and chronic infections. A rec…
Pancreatic cancer kills the vast majority of those diagnosed because it is almost never caught early — but what if the immune system could be primed years befo…
For decades, oncologists have known that some tumors appear to generate their own immune fortresses — organized lymphoid structures that can mount sustained at…
Understanding why leukemia so reliably outsmarts the immune system is one of oncology's most consequential puzzles — and a comprehensive new review in Frontier…
A decades-old surgical assumption — that removing as many lymph nodes as possible improves colorectal cancer outcomes — is now facing a credible biological cha…
Cancer immunotherapy stands at an inflection point: while mRNA vaccine platforms have proven clinically viable, their real-world efficacy has been constrained…
For millions living with autoimmune and chronic inflammatory conditions, the central therapeutic dilemma has long been a brutal trade-off: suppress the immune…
Understanding how the lung repairs and renews itself has profound implications for millions living with chronic respiratory conditions or at elevated cancer ri…
For the decades-long quest to replace uncomfortable tethered endoscopy with something patients will actually tolerate, this research represents a meaningful le…
For decades, one of the most common molecular drivers in prostate cancer has sat beyond the reach of drug developers — not because it was unimportant, but beca…
Breast cancer outcomes are strongly tied to stage at detection, making screening disparities a life-or-death equity issue. Black African women in high-income c…
The boundary between oncology immunotherapy and neurodegenerative disease treatment may be narrowing in a clinically meaningful way. Checkpoint inhibitors — dr…
Precision in radiation therapy hinges on one painstaking step: manually drawing boundaries around tumors and healthy organs on hundreds of CT image slices. For…
The idea of using living organisms as precision cancer-fighting agents is no longer science fiction — it is becoming an increasingly sophisticated engineering…
Spending more does not always mean screening better — and for older women on Medicare, a decade of data reveals a troubling drift toward costlier imaging techn…
HPV vaccination rates remain stubbornly low in parts of the United States, and the COVID-19 pandemic accelerated hesitancy in ways that oncologists and public…
Metastatic castration-resistant prostate cancer carries one of oncology's bleakest prognoses, and the antibody-drug conjugate revolution that reshaped breast a…