Found 1276 results for "longevity"
Scientists identified ribonuclease κ (RNASEK) as a critical enzyme that degrades circular RNAs (circRNAs), which accumulate toxically in aging cells. RNASEK…
Researchers identified MPOL_B_1, a novel geroprotector compound that extends C. elegans lifespan by up to 30% through virtual screening targeting the…
Advanced mapping techniques reveal that sympathetic nerve density increases in aging ovaries across both human and mouse models, with nerve ablation…
Bioengineers have created artificial liver environments using decellularized extracellular matrix scaffolds that successfully induce dormancy in colorectal…
Clinical evidence reveals semaglutide's therapeutic effects extend far beyond its original diabetes indication, with documented benefits across cardiovascular…
CRISPR-edited human cord blood stem cells carrying the GATA2-R398W mutation display severe mitotic dysfunction and accelerated aging signatures that…
The nonoxidative pentose phosphate pathway, orchestrated by enzymes transketolase and transaldolase, emerges as a critical regulator of CD8+ T cell function…
Adult vaccination appears to fundamentally rewire aging immune systems beyond simple pathogen protection, triggering "trained immunity" that reprograms innate…
Analysis of social network data reveals that problematic individuals within close personal circles—termed 'hasslers'—trigger measurable acceleration in…
Chronic kidney disease represents a significant and underrecognized consequence of SARS-CoV-2 infection, with multiple studies demonstrating elevated CKD risk…
Biogerontology researchers argue that extending human healthspan represents a fundamental ethical obligation rather than merely a beneficial outcome. Their…
The LRRC26 auxiliary subunit fundamentally alters how BK potassium channels respond to voltage changes, enabling activation at resting membrane potentials…
Bioengineers developed implantable pressure sensors using liquid metal that wirelessly transmit cardiovascular data without rigid components or external…
Cognitive resilience, autonomic regulation, sleep architecture, and behavioral capacity emerge as the primary determinants of functional longevity, with…
Researchers propose brainspan as a novel metric measuring the duration of life with sufficient neural network efficiency to maintain autonomy, adaptive…
Two years of caloric restriction in healthy adults produced distinct metabolic signatures across 864 circulating compounds, with three major pathway changes…
Muscle stem cells (MuSCs) undergo a fundamental trade-off with aging, prioritizing their own survival over regenerative capacity through increased expression…
Cross-species research reveals that social isolation and loneliness operate through a destructive feedback cycle, where isolation impairs cognitive control…
A cross-sectional analysis of 57 patients who underwent surgical repair for coarctation of the aorta revealed that lower heart rates independently predicted…
The DELTA study introduces a comprehensive N=1 protocol combining time-restricted eating, Mediterranean diet, exercise regimens, and supplementation with…