Found 136 results for "fasting"
A six-month randomized controlled trial examined whether 1.15 grams daily of whole fruit feijoa powder could enhance metabolic benefits of weight loss in 97…
GLP-1 receptor agonists demonstrate striking efficacy in prediabetes reversal, with tirzepatide achieving normoglycemia in 93.3% of patients, semaglutide in…
Understanding why diabetes medications work brilliantly for some patients while failing others could transform personalized treatment approaches. A specific…
Analysis of 8,653 participants followed from birth to age 49, plus 13,795 UK Biobank participants aged 40-79, reveals that metabolic health stratification…
Skeletal muscle-specific deletion of FoxO1, FoxO3, and FoxO4 transcription factors in mice dramatically worsened fatty liver disease during prolonged fasting…
Longevity interventions demonstrate markedly different efficacy between males and females, with response variations potentially linked to baseline lifespan…
The discovery of metabolic master switches often emerges from unexpected cellular machinery. A previously overlooked RNA-binding protein called HuR has now…
Eight months of caloric restriction and resveratrol supplementation failed to prevent functional brain connectivity loss or cognitive decline in TgF344-AD…
A machine learning model successfully predicted which individuals would maintain weight loss 12 weeks after a 5-day fast, using baseline gut microbiome…
Mendelian randomization analysis using genome-wide genetic variants as instrumental variables demonstrates that pescatarian dietary patterns causally reduce…
Environmental toxin exposure may be silently undermining metabolic health in ways that interact dangerously with genetic predisposition and lifestyle choices…
Each hour delay in starting daily food intake was associated with 0.88 mU/l higher fasting insulin, 16.17 mU/l higher post-meal insulin, and 0.30 units higher…
A subtle metabolic marker measured just one hour after glucose intake may identify the optimal window for diabetes prevention efforts. This finding challenges…
The conventional understanding of human motivation may need fundamental revision. Rather than chasing pleasure or subjective rewards, our brains appear…
The transition through menopause brings metabolic shifts that can destabilize weight regulation for decades, yet the hormonal mechanisms governing these…
Astrocytes—the brain's primary support cells—undergo extensive metabolic and structural changes when exposed to ketone therapies including ketogenic diets…
Dietary restriction triggers coordinated activation across seven distinct longevity pathways: autophagy, FGF21 signaling, AMPK activation, mTORC1 suppression…
Retatrutide demonstrates remarkable therapeutic potential by simultaneously targeting three hormone receptors—GLP-1, GIP, and glucagon—achieving weight losses…
The trajectory toward metabolic disease now begins alarmingly early, with profound implications for how parents, educators, and healthcare providers must…
The FAXAge trial will randomize 240 healthy adults over 65 into four groups—exercise alone, time-restricted feeding alone, both interventions combined, or…