DUSP5 Phosphatase Breaks Oncogenic ERK1/2 Feedback Loop in Esophageal Cancer
Esophageal squamous cell carcinoma carries one of the grimmer prognoses in oncology, partly because its molecular drivers remain incompletely mapped. Identifyi…
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Esophageal squamous cell carcinoma carries one of the grimmer prognoses in oncology, partly because its molecular drivers remain incompletely mapped. Identifyi…
For decades, chronic low-grade inflammation in aging adults was treated as a background condition — an unfortunate byproduct of getting older. Emerging evidenc…
Breast cancer diagnosed during or shortly after pregnancy is one of oncology's most vexing challenges — aggressive, understudied, and affecting women at the pe…
Understanding why Americans struggle to eat well — not just whether they have enough food — may be one of the most actionable levers in chronic disease prevent…
For the estimated millions of cancer survivors living with chemotherapy-related cognitive impairment — colloquially called 'chemo brain' — the absence of appro…
For oncologists and patients navigating aggressive cancers, a fundamental question has always been: why do some tumors evolve so rapidly and resist treatment s…
Cell-based drug delivery is one of oncology's most promising frontiers, and a critical safety signal from this first-in-human trial offers a sobering but instr…
GLP-1 receptor agonists — the drug class including semaglutide and liraglutide — appear to reduce risk across at least six obesity-related cancers: prostate, b…
Thymic involution — the progressive shrinkage of the thymus beginning in adolescence — depletes naïve T-cell output, collapses T-cell receptor (TCR) repertoire…
Colorectal cancer's stubborn lethality stems partly from how tumor cells hijack lipid metabolism to fuel their own growth — and a new molecular target in that…
As cancer survival rates climb to historic highs, a growing population of long-term survivors is living with side effects that clinical trials were never desig…
For patients and clinicians hoping that a simple blood draw—or saliva sample, or breath test—could reliably detect lung cancer early, the gap between promising…
Gastric cancer remains one of the most lethal yet preventable malignancies in adults, and the question of whether routine colorectal screening programs could s…
Gastric cancer kills roughly one million people annually worldwide, yet it remains chronically under-screened in Western primary care — largely because clinici…
For the roughly one in five ovarian cancer patients first diagnosed through emergency care rather than planned clinical pathways, the consequences extend far b…
For adults diagnosed with aggressive blood cancers, the promise of targeted immunotherapy can be undermined by the tumor's ability to shed the very protein tha…
The relationship between microbes living inside tumors and cancer biology has been one of the most contested frontiers in oncology over the past decade. Settli…
For patients with one of the rarest and most aggressive blood cancers, treatment options remain desperately limited — and even the one approved therapy fails a…
Understanding how the body ages at a molecular level is one of longevity science's hardest problems — and an unlikely laboratory may accelerate progress. The e…
Pediatric brain cancer treatment has long faced a brutal tradeoff: aggressive therapies that damage developing nervous systems, yet still fail roughly one in t…