Brain-Produced Ketones Enable Neural Activity Independent of Blood Glucose
For over a century, neuroscience has treated the brain as an obligate glucose consumer — a fragile organ that shuts down within minutes when blood sugar…
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For over a century, neuroscience has treated the brain as an obligate glucose consumer — a fragile organ that shuts down within minutes when blood sugar…
At a moment when global health financing is contracting sharply, a three-decade accounting of tuberculosis' toll carries unusual urgency. Understanding…
For the millions of adults living with prediabetes, the conventional focus on diet and exercise may be missing a critical environmental layer. Emerging…
Using two-sample Mendelian randomization mediation analysis across 16 candidate biomarkers, abdominal adiposity—measured as waist-to-hip ratio adjusted for…
Among 7,261 hypertensive adults in the SPRINT trial followed for a median 3.76 years, 174 developed atrial fibrillation. Each of three biomarker domains…
Tuberculosis remains one of the most consequential infectious disease challenges of our era — not because it is newly discovered, but because the gap between…
Oral semaglutide, despite its commercial availability, achieves only 0.4–1% absolute bioavailability under strict fasting conditions — and essentially zero…
The instinct to minimize all sun exposure may be incomplete. A growing body of evidence suggests that the dose-response relationship for ultraviolet radiation…
The timing of food intake is emerging as a variable nearly as consequential as what or how much is eaten — a shift that reframes decades of nutrition research…
Tuberculosis remains one of the most consequential but underappreciated threats to global longevity, and this sweeping analysis arrives at a moment when…
Acute kidney injury following cardiac surgery is one of the most feared postoperative complications, affecting up to 30% of patients and dramatically…
Acute kidney injury following cardiac surgery remains one of the most feared postoperative complications, affecting up to 30% of patients and dramatically…
For millions of adults managing cardiovascular disease, heart failure, or chronic kidney disease alongside diabetes, SGLT2 inhibitors have become cornerstone…
Tuberculosis remains one of the most consequential infectious disease challenges of the modern era, and understanding exactly where progress has stalled — and…
Tuberculosis remains one of the most consequential infectious disease challenges of our era, and at a moment when global health funding is contracting…
With global health funding under unprecedented pressure and WHO's 2035 End TB targets still a distant aspiration for most nations, understanding where…
While global stroke and ischemic heart disease (IHD) mortality dropped 51.7% and 38.2% respectively between 1990 and 2023, Western Sub-Saharan Africa (WSSA)…
Across 25 studies encompassing 356 screened records, semaglutide — a GLP-1 receptor agonist — produced mean weight reductions of 7.6–11.5 kg over 3–6 months…
Tuberculosis remains one of the most consequential infectious disease challenges of the modern era, and a comprehensive new accounting of its toll forces a…
Tuberculosis remains one of medicine's most urgent unsolved problems — not because science lacks tools, but because implementation gaps, funding volatility…