Astronaut Biology Reveals Accelerated Aging Pathways for Earth-Based Therapeutics
The extreme physiological demands of space travel may hold unexpected keys to understanding human aging on Earth. Astronauts experience biological changes in m…
Found 349 results for "longevity"
The extreme physiological demands of space travel may hold unexpected keys to understanding human aging on Earth. Astronauts experience biological changes in m…
A fundamental assumption in cancer biology may need revision: that cellular defects consistently promote or inhibit tumor formation. New findings reveal that d…
The paradox of Asia's respiratory health presents a complex picture for the world's most populous region. While absolute numbers of people living with chronic…
Visual neuroscience has reached a remarkable milestone: the ability to observe individual synapses as they process information from the eye to the brain's visu…
Understanding why some people develop anxiety disorders while others remain resilient may hinge on how quickly the brain's alarm system learns to calm down. Th…
The discovery that specific bacterial toxins create identifiable mutational signatures in human colorectal cancer genomes represents a paradigm shift in unders…
Genetic knockout of the farnesoid X receptor (FXR) dramatically shortened both lifespan and healthspan in male mice, accompanied by accelerated neurodegenerati…
Popular anti-aging supplements could be inadvertently helping one of medicine's most aggressive cancers resist treatment. This discovery challenges the widespr…
Homoharringtonine (HHT), currently FDA-approved for leukemia treatment, selectively eliminates senescent cells in white adipose tissue by binding to heat shock…
Age-related deterioration in sepsis outcomes may stem from fundamental changes in how our gut bacteria interact with intestinal defenses. This mechanistic disc…
Vitamin D supplementation walks a precarious line between therapeutic benefit and serious harm, as demonstrated by a new clinical case that exposes the narrow…
The expanding therapeutic landscape for GLP-1 receptor agonists represents a paradigm shift in treating metabolic dysfunction beyond traditional diabetes manag…
Evolutionary biologist Michael Ringel argues that aging isn't a biological accident but an optimized process shaped by natural selection under resource constra…
Two previously unknown iridoid glycosides from Verbascum nigrum subspecies abietinum activated multiple stress-resistance pathways in C. elegans worms, upregul…
Analysis of 25 rodent longevity models reveals that enhanced blood flow and angiogenesis drive healthful aging in only seven cases, with brown adipose tissue (…
Scientists engineered casein-polyethylene glycol hydrogels using UV-induced crosslinking, achieving 96.31% resveratrol encapsulation efficiency with 86% retent…
Terbinafine, a widely-used antifungal medication, and miglustat, a rare disease treatment, both extended lifespan in C. elegans by activating mitochondrial str…
A systematic analysis of 113 studies reveals that while NAD⁺ precursors like nicotinamide riboside (NR) and nicotinamide mononucleotide (NMN) consistently incr…
Researchers using 5×FAD Alzheimer's mice discovered that dying brain cells release spermidine, a metabolite that triggers autophagy—the cellular cleanup proces…
AI analysis of handheld ultrasound measurements successfully estimated cardiovascular biological age in 243 adults, correlating strongly with chronological age…