Found 1201 results for "longevity"
Physical inactivity constitutes a measurable risk factor for neurodegeneration, with exercise triggering release of dozens of exerkines — bioactive proteins…
Cell membrane architecture may be far more druggable than previously assumed. Lipid rafts — highly ordered microdomains in the plasma membrane — govern how…
Most brain imaging research treats all neural connections as roughly equal — but a neuron firing in your memory center consumes dramatically more energy than…
Why would mescaline in a cactus, psilocybin in a mushroom, and DMT in a jungle vine all activate the same receptor in the human brain? The answer may lie not…
For the roughly 15,000 Americans diagnosed annually with smoldering multiple myeloma, the critical question is not whether they have cancer but when — or…
For decades, aging research catalogued what goes wrong in aging bodies. The 2025 Aging Research and Drug Discovery conference signals a pivotal maturation…
For the hundreds of millions living with psychosis worldwide, the gap between international human rights standards and daily reality remains vast — and…
Spatial proteomics applied to murine colonic mucosa reveals a coordinated cluster of age-associated molecular disruptions: senescent T cells physically…
At 20 mg/kg co-administered with dexamethasone (7 mg/kg IM weekly for 5 weeks) in a rat model, spermidine reversed key markers of glucocorticoid-induced…
A pilot study of 80 healthy Chinese participants across four age cohorts (centered at 10, 30, 50, and 70 years) mapped bacterial and fungal communities on…
Cardiac NAD+ depletion creates a cascade of mitochondrial dysfunction, elevated reactive oxygen species, and cardiomyocyte death — with the rate-limiting…
Pooling 54 prospective and retrospective cohort studies encompassing 1,833,267 participants and 346,034 deaths, this meta-analysis quantifies Mediterranean…
Ovarian aging accelerates through cellular senescence cascades: primordial follicle depletion, SASP-driven stromal inflammation, mitochondrial dysfunction…
In a randomized, double-blind, placebo-controlled substudy of the PROBIOSENIOR trial, 46 adults aged 60+ received either SYNBIO® probiotics at 5×10⁹ CFU daily…
Every decade or so, a technological shift compresses pharmaceutical timelines that once spanned fifteen years into something far shorter. The emergence of…
Copper is one of biology's most paradoxical minerals — essential in trace amounts yet lethal when it accumulates in the wrong cellular compartment. A…
How Americans actually die is more complex than official death statistics suggest — and that gap between recorded data and biological reality has major…
Most people assume a more reactive immune system is unconditionally protective — this research challenges that intuition in a clinically precise way, with…
Screening 991 blood metabolites against cognitive performance and brain MRI markers in 1,082 dementia-free middle-aged participants (Rotterdam Study), this…
Understanding how oxygen levels regulate immune responses could reshape how scientists approach inflammatory diseases and hypoxia-related conditions in humans…