Longevity
mTORC2 Uses Protein Structure, Not Sequence, for Akt Phosphorylation
Researchers discovered that mTORC2 recognizes its key substrate Akt through distant three-dimensional protein structures rather than local amino acid…
Search Results: "cancer"
Found 1858 results for "cancer"
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Longevity
SIRT6 Protein Controls Mitochondrial Function Through Dual Nuclear-Mitochondrial Pathway
The discovery that cellular aging processes operate through coordinated nuclear-mitochondrial communication pathways could reshape therapeutic approaches to…
PREPRINTWellbeing
Childhood Cancer Treatment Impairs Endothelial Repair Through Senescent Cell Accumulation
Researchers tracked endothelial injury markers in 48 children with leukemia and lymphoma receiving anthracycline chemotherapy, measuring circulating…
Studies
Young Colorectal Cancer Patients Show Higher Family History, More Left-Sided Tumors
Rising early-onset colorectal cancer rates demand closer examination of how the disease manifests differently across age groups, particularly as younger…
Studies
miRNA-126 Inhibitor miRisten Boosts Venetoclax Efficacy Against Leukemic Stem Cells
Targeting the metabolic machinery that fuels cancer stem cells represents a critical frontier in treating acute myeloid leukemia, where resistant stem cell…
Studies
Ovarian Cancer's Immune Evasion Mechanisms Reveal New Therapeutic Vulnerabilities
Ovarian cancer's notorious resistance to treatment stems from sophisticated immune evasion tactics that could paradoxically become its downfall. While…
Studies
AI-Enhanced Blood Test Detects Cancer With 97% Accuracy Across Ten Types
The pursuit of a universal cancer screening test has moved significantly closer to reality with breakthrough technology that could transform early detection…
Studies
Specific Gut Bacteria Drive Colorectal Cancer Through Secondary Bile Acids
The longstanding question of whether Western diets directly fuel colorectal cancer through gut bacterial metabolism has finally received definitive…
Supplements
Resveratrol Shows Anticancer Promise Across Multiple Cancer Types via Apoptosis and Other Pathways
Resveratrol demonstrates anticancer activity across nine distinct cancer types—including breast, prostate, colon, and brain cancers—by triggering cell cycle…
Longevity
Life's Simple 7 Cardiovascular Score Associated with 38% Lower All-Cause Mortality in Cancer Survivors
Cancer survivors following the American Heart Association's Life's Simple 7 cardiovascular health guidelines experienced a 38% reduction in all-cause…
Studies
Global Gastrointestinal Cancer Cases Expected to Nearly Double by 2050
The emerging global health crisis extends far beyond current cancer statistics, fundamentally reshaping how healthcare systems must prepare for an…
Longevity
Breast Tissue Epigenetic Age Clocks Predict Cancer-Risk Metabolic Markers
Researchers measured DNA methylation patterns in normal breast tissue from 91 cancer-free women using five different epigenetic age clocks, finding that…
Wellbeing
Indoor Radon Above 200 Bq/m³ Correlates Strongly with Regional Lung Cancer Rates
Home air quality emerges as a measurable factor in cancer geography, with new evidence quantifying how residential radon levels predict regional lung cancer…
Studies
New Statistical Method Unlocks Rare Genetic Variants in Disease Timing
The timing of disease onset may hold crucial clues for extending healthy lifespan, but until now, researchers lacked effective tools to analyze how rare…
Studies
Cellular Protein Rabankyrin-5 Controls HPV Entry Into Host Cells
Understanding how viruses hijack cellular machinery could unlock new therapeutic strategies for preventing persistent infections that lead to cancer. Human…
Studies
Cholesterol Drug Fluvastatin Blocks Breast Cancer Growth Through CYP4Z1 Enzyme
The discovery that a widely-prescribed cholesterol medication can interfere with breast cancer development opens new possibilities for repurposing existing…
Studies
Hormone Therapy Shows Safety Profile for Most Gynecologic Cancer Survivors
Cancer survivorship increasingly means navigating decades of post-treatment life, yet many gynecologic cancer survivors face an unexpected dilemma: managing…
Studies
NLRX1 Protein Controls Mitochondrial Death Switch in Human Cells
A critical cellular death mechanism just became clearer, potentially opening new therapeutic avenues for age-related diseases and neurodegeneration…
Studies
Specific Paracancerous Tissue Bacteria Predict Lung Cancer Immunotherapy Success Rates
The ability to predict which lung cancer patients will respond to immunotherapy could transform treatment decisions for thousands of patients annually…
Studies
CAR-T Therapy Shows Superior Response Rates Over Bispecific Antibodies
Cancer patients facing treatment-resistant lymphomas now have clearer guidance on which advanced immunotherapy offers better odds of remission. Two…