Pembrolizumab-Paclitaxel Combination Wins FDA Approval for PD-L1 Positive Ovarian Cancer
The FDA has authorized pembrolizumab combined with paclitaxel, optionally with bevacizumab, for treating recurrent ovarian cancers expressing PD-L1 protein. Th…
Found 1465 results for "cancer"
The FDA has authorized pembrolizumab combined with paclitaxel, optionally with bevacizumab, for treating recurrent ovarian cancers expressing PD-L1 protein. Th…
Analysis of 85,000 older adults in the UK reveals that accumulated daily movement—including light activities like walking or household tasks—provides measurabl…
Tumor infiltrating lymphocyte (TIL) therapy combined with checkpoint inhibitors achieved substantial tumor regression across multiple metastatic gastrointestin…
National cancer registry data reveals mortality declined at 2.1% annually for men and 1.4% for women from 2001-2022, maintaining trajectory even through 2020-2…
National Cancer Institute surveillance data spanning 2010-2019 reveals a striking bifurcation in early-onset malignancies: while 14 cancer types increased in a…
NIH investigators identified specific tissue alterations that predict both aggressive breast cancer development in women with benign breast conditions and wors…
A comprehensive WHO analysis examining 30 modifiable risk factors reveals that 40% of global cancer cases stem from preventable causes, representing the most e…
Analysis of 7,619 East Asian genomes identified nearly 29,000 novel methylation quantitative trait loci (mQTLs) that regulate DNA methylation patterns differen…
Mendelian randomization analysis of 738,000 individuals confirms that elevated BMI causally increases kidney cancer risk by 68% per 5-unit BMI increase, with w…
vCATCH technology achieves single-cell resolution mapping of covalent drug binding sites across intact mammalian tissues, offering unprecedented visualization…
Enzalutamide, an androgen receptor inhibitor, demonstrated significant survival benefits in men with biochemically recurrent prostate cancer following initial…
University of South Florida researchers identified elevated omega-6 fatty acid concentrations within colorectal tumor tissue, demonstrating a direct inflammato…
Clinical evidence demonstrates that subsidized fruit and vegetable programs yield quantifiable health improvements across diverse populations. Participants rec…
Metastatic cancer cells actively acquire mitochondria from surrounding immune cells through a previously uncharacterized transfer mechanism, essentially comman…
The MET-PREVENT trial enrolled over 1,000 participants to test whether metformin could delay onset of cardiovascular disease, cancer, dementia, and other age-r…
Age-related decline in natural killer cell function stems from disrupted glycolysis and mitochondrial metabolism, according to new mechanistic research. Scient…
Platinum chemotherapy triggers cellular senescence in ovarian and lung cancer cells, paradoxically promoting malignancy through TGFβ ligand secretion. González…
Researchers have developed methods to selectively eliminate specific populations of senescent cells while preserving those that contribute to tumor suppression…
The dual-drug approach combining trastuzumab deruxtecan with pertuzumab demonstrated enhanced progression-free survival compared to standard HER2-targeted ther…
Economic modeling across four Pacific Island nations reveals that rotavirus, pneumococcal conjugate, and human papillomavirus vaccines provide substantial cost…