Engineered Salmonella Creates Tumor Blood Clots Through Vascular Entrapment
Live imaging of tumor blood vessels reveals that engineered Salmonella strain YB1 gets physically trapped in the chaotic architecture of cancer vasculature, pa…
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Live imaging of tumor blood vessels reveals that engineered Salmonella strain YB1 gets physically trapped in the chaotic architecture of cancer vasculature, pa…
Senescent cells in mammary tissue serve opposing roles during the critical postpartum period, promoting healthy breast remodeling under normal circumstances wh…
An 18-year mortality analysis reveals elevated cancer death rates in U.S. counties positioned closer to operational nuclear facilities, with the effect most pr…
Mathematical modeling reveals that metastatic prostate cancer can be managed by deliberately guiding tumor evolution rather than attempting maximum cell kill.…
Advanced gas sensor arrays analyzing volatile organic compounds in plasma successfully distinguished between ovarian cancer, endometrial cancer, and healthy co…
The AMPLITUDE phase 3 trial demonstrated that adding niraparib to standard hormone therapy significantly extends time to cancer progression in men with metasta…
Computer-assisted screening platforms using whole slide imaging and artificial intelligence are demonstrating viable performance characteristics for Pap test a…
Radiation therapy triggers senescence in thyroid cancer cells, but these supposedly dormant cells develop a cunning survival strategy. When radiation disrupts…
Researchers identified that amlodipine, a widely prescribed calcium channel blocker for hypertension, demonstrates significant anti-tumor activity against hepa…
Researchers analyzed 215 studies examining artificial intelligence applications in diffuse large B-cell lymphoma (DLBCL) prognosis, revealing that machine lear…
Analysis of 798 testicular cancer survivors reveals that four cycles of etoposide-cisplatin (EPx4) produce 55% higher odds of kidney impairment compared to thr…
Analysis of 17,141 survivors across seven cancer types reveals that moderate-to-vigorous physical activity after diagnosis reduces cancer-specific mortality by…
Mediterranean and low-carbohydrate diets combined with exercise significantly reduced cardiovascular and metabolic risk factors in prostate cancer patients rec…
Analysis of Japan's national disease registry identified pseudo-polyps as tripling colorectal cancer risk in ulcerative colitis patients (hazard ratio 2.92), w…
Thyroid nodules develop in 2-3% of pregnancies, with existing nodules often enlarging due to hormonal changes that naturally increase thyroid gland size. Fine…
Scientists developed a molecular adapter called eCD16A/anti-CD3-BFP that transforms existing cancer antibodies into T cell-recruiting weapons. The bifunctional…
Scientists have developed genetically modified immune cells that specifically target amyloid-beta plaques in Alzheimer's disease. These engineered CD4+ T cells…
Scientists achieved cognitive restoration in aged and Alzheimer's disease mice by applying OSK transcription factor therapy specifically to engram neurons—the…
A compound initially identified in cancer drug screening has demonstrated dual efficacy against Huntington's disease pathology and calcium oxalate kidney stone…
Researchers have developed a novel approach using genetically modified megakaryocytes to generate cancer-fighting platelets directly within the bloodstream. Th…