Found 1137 results for "cancer"
Metastatic melanoma cells exhibit elevated levels of lamin B receptor (LBR), a nuclear envelope protein that paradoxically makes their nuclei more fragile when…
MYCN, a master regulator oncogene, demonstrates specific transcriptional control mechanisms in hepatocellular carcinoma development, with researchers mapping i…
Circulating tumor DNA analysis in blood and urine samples successfully identifies which muscle-invasive bladder cancer patients can avoid radical cystectomy wh…
Chimeric antigen receptor natural killer (CAR-NK) cells demonstrate significantly reduced cytokine release syndrome and neurotoxicity compared to CAR-T therapi…
Mammary gland involution following weaning triggers widespread cellular senescence that orchestrates tissue remodeling but simultaneously creates microenvironm…
The PRIME trial found that biparametric MRI (bpMRI) performs equivalently to the standard multiparametric MRI (mpMRI) for detecting clinically significant pros…
Recent trial data indicates that biparametric MRI (bpMRI), which uses only two imaging sequences instead of the standard three or more, demonstrates equivalent…
Dimethyl sulfoxide-frozen platelets demonstrated equivalent hemostatic efficacy to standard liquid-stored platelets in controlling bleeding during cardiac surg…
The PRIME clinical trial establishes that biparametric MRI (bpMRI) achieves equivalent diagnostic performance to multiparametric MRI (mpMRI) for identifying cl…
Breast, colorectal, lung, brain, and lymphoid cancers account for approximately 70% of cancer deaths in Americans under 50, with colorectal cancer showing part…
Declining donor populations and platelets' 5-7 day shelf life have created critical transfusion shortages worldwide, particularly affecting cancer patients and…
Medical experts are raising concerns about potential policy changes that could weaken universal hepatitis B vaccination for newborns, currently recommended by…
A randomized trial of 190 frail elderly patients with head and neck cancer found that hypofractionated split-course radiotherapy achieved equivalent 6-month tu…
Pooled analysis of eight randomized trials involving 749 advanced lung cancer patients demonstrates that structured exercise interventions produce a standardiz…
A cytoplasmic enzyme called N4BP2 has been identified as a key driver of catastrophic chromosome shattering in cancer cells. This nuclease enters ruptured micr…
Pancreatic cancer cells establish direct synaptic-like connections with sensory neurons, utilizing glutamate receptors typically found in the brain to accelera…
Nondaily and low-intensity smokers in Latin America present distinct cessation challenges that differ markedly from heavy daily users. These lighter smoking pa…
Scientists achieved cognitive restoration in aged and Alzheimer's disease mice by applying OSK transcription factor therapy specifically to engram neurons—the…
Scientists have developed genetically modified immune cells that specifically target amyloid-beta plaques in Alzheimer's disease. These engineered CD4+ T cells…
Economic modeling across four Pacific Island nations reveals that rotavirus, pneumococcal conjugate, and human papillomavirus vaccines provide substantial cost…