Dual-Compartment Yeast Engineering Yields 552 mg/L Resveratrol via Peroxisome Factory
A dual-compartment metabolic engineering strategy simultaneously activated resveratrol biosynthesis in both the peroxisomes and cytoplasm of Saccharomyces…
Found 1276 results for "longevity"
A dual-compartment metabolic engineering strategy simultaneously activated resveratrol biosynthesis in both the peroxisomes and cytoplasm of Saccharomyces…
Across three cohorts totaling 1,462 adults, a Bayesian ridge regression model applied to resting-state fMRI data produced a Brain Aging Index (BAI) — the…
Understanding how omega-3 fatty acids exert their well-documented anti-inflammatory and metabolic benefits has long been an incomplete picture. A molecular…
For families living with sickle cell disease or beta-thalassemia, the prospect of a one-time curative intervention has shifted from theoretical to…
Multiple myeloma remains one of the most complex hematologic malignancies to manage, not because effective drugs are lacking, but because the rapidly…
Population-scale health data has long been constrained by cohort sizes too small to detect rare disease patterns or meaningful demographic subgroup…
Growth-related knee pain is quietly undermining youth athletic development, yet the field has lacked good data on which modifiable factors actually drive…
Cholesterol management inside cells is far more intricate than blood lipid numbers suggest, and a new class of molecular tools may redefine how researchers…
How the brain fuels its own activity at the level of individual cells has remained one of neuroscience's most technically intractable questions. A new imaging…
A purified homogalacturonan-type pectin polysaccharide, AAP50-2, isolated from the traditional Chinese herb Anemarrhena asphodeloides, extended maximum…
Every cell in the human body relies on a molecular machine called cytochrome bc1 to convert food into usable energy — and for decades, exactly how this…
Understanding how mitochondrial DNA mutations translate into real cellular dysfunction has been one of the most stubborn technical gaps in aging and metabolic…
GLP-1 receptor agonists have reshaped obesity and diabetes medicine, but a deeper question has lingered: are their wide-ranging benefits incidental side…
The assumption that aging muscles simply need more thyroid hormone to regenerate effectively has guided clinical thinking for decades — and may be…
Personality has long occupied an uneasy middle ground between biology and biography — shaped by genes, upbringing, culture, and chance in ways that were…
Heart failure and cardiac aging have long been linked to declining mitochondrial function, but the precise causal chain — from DNA-level mutations inside…
For decades, global health policy has organized disease priorities around infectious versus chronic illness — a binary that increasingly fails to capture how…
Male reproductive aging has long been attributed primarily to testicular decline, but a growing body of evidence suggests the epididymis — the tubular…
Transgenic mice expressing a growth hormone receptor antagonist (GHA) — engineered via a glycine-to-lysine mutation at position 120 of human GH — lived…
For adults seeking evidence-based strategies to preserve physical capacity into old age, the master athlete model offers one of the most compelling natural…