New Statistical Tool Establishes Causal Gene Regulation From CRISPR Screen Data
Most genomic research can tell us which genes move together — but not which ones actually drive the others. That distinction matters enormously for drug…
Found 1201 results for "longevity"
Most genomic research can tell us which genes move together — but not which ones actually drive the others. That distinction matters enormously for drug…
One of evolutionary biology's most contested ideas — that boldness, longevity, and fertility are biologically yoked together rather than independently tunable…
Age-related macular degeneration remains one of the leading causes of irreversible vision loss in older adults, and oxidative damage to the eye's delicate…
Falls remain one of the leading causes of injury-related death and disability in adults over 65, yet decades of prevention campaigns have barely moved the…
As global populations age and multimorbidity becomes the norm rather than the exception, the question of how to effectively support both patients and their…
Chronic insomnia does more than exhaust the body — it may accelerate the molecular machinery of aging itself. The idea that treating a common sleep disorder…
For decades, metformin has attracted intense interest as a potential longevity-extending compound beyond its glucose-lowering role — a hypothesis now being…
For decades, the implicit assumption in aging research has been that surviving to extreme old age confers a kind of biological resilience that erases earlier…
The intense scientific interest in repurposing a decades-old diabetes drug as a broad anti-aging intervention has reached a critical inflection point. A…
Among the most consequential open questions in dementia research is whether the genetic risk architecture established in midlife continues to operate the same…
For decades, the idea of training the immune system to recognize and destroy a patient's own tumor has tantalized oncologists — yet only one therapeutic…
Understanding how life's molecular machinery originated touches one of the deepest questions in biology — and now carries surprising implications for…
Personalized medicine is reaching geroscience in a meaningful way, and PROMETHEUS represents one of the more structured attempts to operationalize that idea…
Chronic low-grade inflammation — sometimes called 'inflammaging' — is one of the most consequential features of biological aging, linked to everything from…
Among 311 postpartum women in the PETALS-2 prospective cohort, each one-unit increase in intrinsic motivation (IM) score was associated with 42% greater…
Among 300,927 adults undergoing transcatheter aortic valve replacement (TAVR) between 2010 and 2026, cumulative reintervention incidence reached only 2.7% at…
When a single chronic disease rarely arrives alone, clinical management becomes exponentially more complex — and for the tens of millions of older adults…
Cardiovascular disease remains the leading cause of death globally, and lipid management sits at the center of prevention strategy. When the American College…
The composition of trillions of microbes lining the human gut turns out to be far more than a digestive footnote — it may be a central orchestrator of how…
Autophagy within hypothalamic NPY+/AGRP+ neurons governs hippocampal presynaptic active zone architecture and proteostasis through non-cell autonomous…