Found 1276 results for "longevity"
What separates those who thrive in their late eighties from those who merely survive may have less to do with physical capacity than previously assumed. For…
As semaglutide and tirzepatide reshape obesity medicine, a critical question has emerged that the weight-loss headlines routinely bury: what happens to the…
Semaglutide and related GLP-1 receptor agonists are producing mortality and organ-protection effect sizes that outpace what glycemic control or weight loss…
Circulating and intrahepatic Hepassocin (HPS) levels decline with age in both mice and elderly humans, and this drop directly impairs hepatic regeneration. In…
IGFBP5 expression drops significantly in dental follicle stem cells (DFSCs) undergoing both replicative and oxidative (H₂O₂-induced) senescence. Restoring…
When nearly one million deaths cluster around two of the most feared conditions in aging — stroke and dementia — the trajectory of those deaths matters…
Vaccine durability and long-term protection from infection depend not just on whether antibodies are made, but on how long plasma cells survive in the bone…
The relationship between growth hormone signaling and aging has long intrigued longevity researchers, but translatable pharmacological tools have remained…
For the millions of older adults who take statins not because they've had a heart attack but simply as a preventive measure, a foundational question has gone…
Tuberculosis remains one of the most consequential infectious disease challenges of our era — and a major new systematic analysis now provides the most…
A clinical trial measuring 11 fecal metabolites found that regulated walnut intake was associated with a 2.8% increase in gut microbial alpha diversity, a…
Most GLP-1 drugs are prescribed for blood sugar and weight — but if their longevity effects in mammals generalize beyond metabolic disease, the implications…
The GLP-1 drug class has rapidly transformed metabolic medicine, but a fundamental question has lingered: are its benefits simply downstream of weight loss…
Population growth is quietly erasing decades of public health victories against tobacco exposure. Even as age-standardised rates of second-hand smoke (SHS)…
Most drugs tested against age-related diseases are never evaluated for whether they also slow biological aging itself — a missed opportunity that could…
At an optimal concentration of 0.2 μM, cycloastragenol (CAG) — a triterpenoid extracted from Astragalus membranaceus — extended mean lifespan in C. elegans by…
A pilot single-arm trial administered 1 mg/day rapamycin for 4 weeks to 23 cognitively normal adults aged 45–65, stratified by APOE4 genotype. Among the nine…
What if the immune system held the master key to living past 100 in good health? A comprehensive review in Nature Reviews Immunology makes a compelling case…
A whole-food, plant-predominant diet (WFPD) delivers broad cardiometabolic and mental health benefits through multiple converging mechanisms: enhanced…
Among 101 multicellular species capable of living 250 years or longer — 11 animals and 90 plants — a systematic survey of genetic, transcriptomic, proteomic…