Found 1276 results for "longevity"
For decades, oncology has been constrained by a fundamental limitation: roughly 80% of disease-driving proteins are structurally unsuited to conventional…
What separates people who reach 100 from those who don't may have less to do with luck and more to do with a suite of measurable, interconnected immune…
For adults tracking their biological age, the quality of their nightly sleep may matter as much as diet or exercise — and now there is a molecular explanation…
Mental health conditions now represent one of the most consequential sources of disability-adjusted life lost worldwide — yet their true epidemiological…
Mental illness is not a crisis unfolding in isolation — it is a measurable, quantifiable pandemic tracked across 204 countries. Understanding its true scale…
Metabolic-associated fatty liver disease now affects roughly one-third of adults globally, yet approved pharmacological options remain limited. A mechanistic…
Polyamines — small, positively charged metabolites including spermidine and spermine — have long been recognized for supporting ribosomal translation…
Bound polyphenols extracted from carrot dietary fiber (CDF-BP) extended mean lifespan in Caenorhabditis elegans by 25.58% at a concentration of 50 μg/mL…
Feeding Caenorhabditis elegans the magnetotactic bacterium Magnetospirillum magneticum AMB-1 extended mean lifespan by 43.4% — from 17.17 to 24.62 days…
Mild hypoxia, induced by low-dose cobalt chloride (CoCl2) in C. elegans, significantly extended healthspan — measured as sustained locomotor activity and…
Germline deletions of the UDP-glycosyltransferase genes UGT2B17 and UGT2B28 — affecting androgen and steroid metabolism — show sex-differentiated associations…
A phenotypic cell-based screen designed to detect compounds that shift mRNA translation toward short 5'-UTR transcripts — mimicking dietary restriction and…
The persistence of meningitis as a major global killer reveals troubling gaps in our public health infrastructure, particularly for protecting the world's…
The ability to predict who will develop chronic diseases decades before symptoms appear represents a transformative shift from reactive to preventive…
The conventional view treats Parkinson's disease as an isolated brain disorder, but emerging evidence reveals a broader aging cascade that simultaneously…
The aging brain's vulnerability to structural decline may have a powerful ally in vitamin C, with implications extending far beyond traditional antioxidant…
Arsenic exposure triggers liver fibrosis by disrupting the SIRT1/C/EBPα signaling axis, which normally regulates bile acid detoxification. The study…
Cellular energy production may be more flexible than previously understood, with implications for metabolic health and aging interventions. The mitochondrial…
The transformation of sesame seeds during sprouting reveals sophisticated biochemical machinery that could unlock new therapeutic compounds for human health…
The fundamental assumption that DNA recognition requires unwinding has been challenged by compelling evidence that intact double helices can directly identify…