First Hippo-YAP-TEAD Pathway Drug Shows 32% Response Rate in Mesothelioma
VT3989 achieved a 32% overall response rate with 86% disease control in mesothelioma patients when optimal dosing and monitoring protocols were applied, markin…
Found 573 results for "cancer"
VT3989 achieved a 32% overall response rate with 86% disease control in mesothelioma patients when optimal dosing and monitoring protocols were applied, markin…
The devastating fatigue and diminished quality of life that accompany breast cancer chemotherapy may no longer be inevitable consequences patients must simply…
Rezatapopt demonstrates the ability to restore function to a specific p53 mutation (Y220C) found in roughly 100,000 cancer patients annually. This small-molecu…
The combination of amivantamab and lazertinib demonstrates therapeutic potential in patients with EGFR-mutated advanced non-small cell lung cancer, targeting b…
A therapeutic compound successfully reactivated mutated p53 protein function in solid tumors, targeting one of the most common genetic alterations in human can…
A critical cellular death mechanism just became clearer, potentially opening new therapeutic avenues for age-related diseases and neurodegeneration. Scientists…
Taiwanese women born after 1975 in cities and 1980 in rural areas show dramatically elevated cervical cancer risks compared to earlier generations, with urban…
Analysis of HPV vaccination data across 28 Malawian districts from 2019-2024 reveals concerning coverage gaps, with first-dose uptake at 47% and second-dose co…
Cryo-electron microscopy revealed how phosphatidylinositol 4-phosphate (PI4P) and the experimental compound GNE-6468 work together to activate STING, a crucial…
Analysis of cervical cancer tissues from 40 Palestinian women revealed HPV infection in 82.5% of cases, with high-risk strains accounting for 77.5% of detectio…
Histotripsy demonstrated an 82.5% efficacy rate at one month when treating 60 liver tumors across 30 patients, using focused ultrasound waves to mechanically d…
Live imaging of tumor blood vessels reveals that engineered Salmonella strain YB1 gets physically trapped in the chaotic architecture of cancer vasculature, pa…
The discovery that common herpes viruses manipulate a specific cellular enzyme to trigger cancer represents a significant advance in understanding virus-driven…
An 18-year mortality analysis reveals elevated cancer death rates in U.S. counties positioned closer to operational nuclear facilities, with the effect most pr…
Despite comprising 40% of US cancer cases, adults over 70 remain significantly underrepresented in oncology research and care optimization, with fewer than 3%…
Analysis of multisite hospital records reveals individuals with recurrent Clostridioides difficile infections face a 105% increased risk of developing colorect…
Non-medical community workers trained in symptom monitoring significantly reduced emergency department visits and hospitalizations among older cancer patients…
Telephone-based symptom monitoring by trained community health workers reduced emergency department visits and hospitalizations by 28% among adults over 65 wit…
Senescent cells in mammary tissue serve opposing roles during the critical postpartum period, promoting healthy breast remodeling under normal circumstances wh…
Mathematical modeling reveals that metastatic prostate cancer can be managed by deliberately guiding tumor evolution rather than attempting maximum cell kill.…