Sirt3 Activation Reverses Disc Degeneration via Mitochondrial Calcium and ATP Pathways
Low back pain costs the global economy hundreds of billions of dollars annually and affects roughly 80% of adults at some point in their lives — yet most…
Found 1276 results for "longevity"
Low back pain costs the global economy hundreds of billions of dollars annually and affects roughly 80% of adults at some point in their lives — yet most…
One of the quieter tragedies of aging is the gradual collapse of immune competence — not from a single failure but from a slow drift in how blood stem cells…
For anyone tracking the frontiers of Alzheimer's, Parkinson's, or ALS research, a single technology that could simultaneously detect disease earlier and…
Across 16 trials pooled in this systematic review and meta-analysis, exercise interventions in older adults produced meaningful but modest gains in gut…
The biological mechanisms linking amyloid precursor protein (APP) processing to early synaptic failure in Alzheimer's disease have long eluded researchers…
Understanding why some people respond to anti-inflammatory drugs while others develop resistance or serious side effects may come down to a single molecular…
Pooling 17 in vitro studies using human-derived cell models, this meta-analysis found that GLP-1 receptor agonists — the drug class including semaglutide…
ASAP3, an actin cytoskeleton remodeling protein, is upregulated in aged mouse livers and H₂O₂-stressed hepatocytes. Its genetic knockout extended lifespan…
Chronic low-grade inflammation driven by dietary advanced glycation end products (AGEs), lipid peroxidation products, oxysterols, trans fats, and…
Global grain harvests face mounting pressure from rising temperatures, and wheat — a caloric cornerstone for more than a third of humanity — is among the most…
Understanding what happens in cardiac tissue after a heart attack has entered a new level of molecular resolution — and the implications extend far beyond the…
A Bayesian Markov generator-matrix model fitted to NHANES (n=23,844) and replicated in the Health and Retirement Study finds that approximately 92% of…
The assumption that dengue fever is a traveler's disease returnable from the tropics is quietly eroding. Southern Europe is undergoing a measurable…
About 70% of all breast cancer diagnoses are estrogen receptor-positive, yet the field's workhorse preclinical system — the genetically engineered mouse — has…
A persistent mismatch between rising mental health demand and a shrinking clinical workforce has made digital augmentation not just convenient but…
A multinational consensus from three major European obesity and nutrition bodies — EASO, EFAD, and ECPO — synthesizes pragmatic clinical guidance for managing…
Idiopathic pulmonary fibrosis remains one of the most feared progressive lung diseases in adults over 60, with a median survival historically measured in…
Chronic kidney disease sits at a troubling intersection of modern health challenges — it is largely silent until advanced, disproportionately tied to diabetes…
The gap between chronological age and biological age may be one of the most clinically actionable gaps in modern medicine — and a comprehensive new review in…
Understanding why some people live past 100 while maintaining cellular integrity has long been one of longevity biology's most tantalizing puzzles. New…