Found 573 results for "cancer"
GLP-1 receptor agonists demonstrate therapeutic effects extending far beyond their established role in diabetes and obesity management, operating through multi…
Bladder cancer patients now have access to precision medicine approaches that were unimaginable just a decade ago, fundamentally changing treatment decisions a…
Cancer treatment may be entering a new era with the targeting of metabolic pathways that tumors hijack for survival. The peroxisome proliferator-activated rece…
Advanced bladder cancer patients who cannot tolerate standard chemotherapy have long faced limited treatment options before undergoing radical surgery. This po…
The most lethal childhood brain cancers may finally have met their match through a precision epigenetic approach that dismantles the molecular machinery keepin…
The precision medicine revolution in melanoma treatment hinges on understanding which genetic drivers fuel individual tumors, yet comprehensive molecular profi…
Traditional anti-inflammatory drug development has hit a fundamental wall: targeting single molecules in complex immune cascades repeatedly fails in clinical t…
Medical systems worldwide face a staggering reality: sepsis accounts for nearly one-third of all deaths globally, making it potentially the leading cause of mo…
Pancreatic cancer cells exploit the UBE3A protein to resist cellular senescence by degrading mH2A1 histone variants at the K167 residue, which normally suppres…
The path from pancreatic injury to cancer may be more predictable than previously understood, potentially opening new windows for early intervention in one of…
The timing of disease onset may hold crucial clues for extending healthy lifespan, but until now, researchers lacked effective tools to analyze how rare geneti…
Female mice generated significantly stronger antibody responses to influenza vaccination than males through estradiol-driven metabolic reprogramming of B cells…
For patients facing muscle-invasive bladder cancer, the standard treatment often means losing their bladder entirely through surgical removal. This aggressive…
Metabolic dysfunction-associated steatotic liver disease affects nearly one billion people globally, yet therapeutic options remain limited despite the conditi…
The FABULOUS trial demonstrates that combining fuzuloparib (a PARP inhibitor) with apatinib (an angiogenesis inhibitor) significantly improves progression-free…
The MetaCURE trial tested an intensive multimodal approach combining apalutamide-based hormone therapy, surgical resection, and targeted radiation in 65 men wi…
Three-dimensional laboratory models incorporating patient-derived tissues now replicate the complex cellular environment surrounding triple-negative breast can…
Analysis of 801 multiple myeloma patients revealed that 8.7% developed atrial fibrillation after autologous stem cell transplantation, with median onset occurr…
Medicare patients who underwent colon or lung cancer surgery at hospitals that eventually closed experienced significantly worse outcomes compared to those tre…
CRISPR-edited human cord blood stem cells carrying the GATA2-R398W mutation display severe mitotic dysfunction and accelerated aging signatures that compromise…