Found 349 results for "longevity"
Kidney disease affecting one in every 200 adults globally now has fundamentally updated treatment protocols that shift from symptom management to targeting und…
Finding reliable biomarkers of aging remains one of the most challenging puzzles in longevity research, with most studies limited to single tissues or time poi…
The translation of promising anti-aging compounds from laboratory to clinic faces a critical bottleneck: the absence of validated biomarkers to measure cellula…
Blood stem cells carrying faulty p53 genes may exploit the body's inflammatory responses to gain an unfair survival advantage, potentially explaining why certa…
Two compounds increasingly popular among longevity enthusiasts may work through fundamentally different cellular pathways, suggesting strategic timing and comb…
The silent epidemic of gout is reshaping global health patterns, with 57 million people now living with this painful joint condition that disproportionately st…
The trajectory of human cardiovascular health reveals a sobering paradox: despite decades of medical advances and prevention campaigns, the global burden of he…
The most metabolically resilient animals on Earth may hold keys to solving humanity's most stubborn health challenges. From bears that emerge from months-long…
The relationship between metabolic rate and body size may be far more complex than previously understood, with profound implications for how we interpret energ…
Understanding how neurons control their electrical activity becomes increasingly critical as we age, since disrupted neural excitability underlies conditions f…
Understanding how cells manufacture DNA building blocks has taken a significant leap forward with new insights into ribonucleotide reductase, the enzyme respon…
High glucose levels accelerate bone marrow mesenchymal stem cell senescence through a newly identified Mettl3/Foxo3/Sirt1 molecular axis. In diabetic mice, hyp…
Understanding how immune cells maintain tissue health could unlock new approaches to inflammatory diseases and age-related tissue dysfunction. Macrophages serv…
The FAXAge trial will randomize 240 healthy adults over 65 into four groups—exercise alone, time-restricted feeding alone, both interventions combined, or cont…
Eleutheroside B, a compound from Siberian ginseng, dramatically reduced amyloid-beta and tau protein accumulation while improving cognition and lifespan in tra…
Lin's research reveals a sophisticated glucose-sensing mechanism where the AXIN:LKB1 complex translocates to lysosomal surfaces when aldolase detects low gluco…
Aspartame at 100 μM concentrations activated autophagy genes (bec-1, unc-51, lgg-1, lgg-2, atg-5) in C. elegans worms, extending lifespan while enhancing resis…
The explosive rise in ultra-processed food consumption across Europe represents a fundamental shift in cancer risk that most adults underestimate. These conven…
Injectable thermosensitive hydrogels delivering resveratrol demonstrate significant cartilage protection in mouse osteoarthritis models by activating SIRT1 and…
Freshly minced dental pulp tissue generated well-organized dentin-pulp-like structures with high cellularity, vascularization, and mineral deposits in mice, si…