Found 1276 results for "longevity"
As global populations age and multimorbidity becomes the norm rather than the exception, the question of how to effectively support both patients and their…
Chronic insomnia does more than exhaust the body — it may accelerate the molecular machinery of aging itself. The idea that treating a common sleep disorder…
For decades, metformin has attracted intense interest as a potential longevity-extending compound beyond its glucose-lowering role — a hypothesis now being…
For decades, the implicit assumption in aging research has been that surviving to extreme old age confers a kind of biological resilience that erases earlier…
The intense scientific interest in repurposing a decades-old diabetes drug as a broad anti-aging intervention has reached a critical inflection point. A…
Among the most consequential open questions in dementia research is whether the genetic risk architecture established in midlife continues to operate the same…
For decades, the idea of training the immune system to recognize and destroy a patient's own tumor has tantalized oncologists — yet only one therapeutic…
Understanding how life's molecular machinery originated touches one of the deepest questions in biology — and now carries surprising implications for…
Personalized medicine is reaching geroscience in a meaningful way, and PROMETHEUS represents one of the more structured attempts to operationalize that idea…
Chronic low-grade inflammation — sometimes called 'inflammaging' — is one of the most consequential features of biological aging, linked to everything from…
Among 311 postpartum women in the PETALS-2 prospective cohort, each one-unit increase in intrinsic motivation (IM) score was associated with 42% greater…
When a single chronic disease rarely arrives alone, clinical management becomes exponentially more complex — and for the tens of millions of older adults…
Cardiovascular disease remains the leading cause of death globally, and lipid management sits at the center of prevention strategy. When the American College…
The composition of trillions of microbes lining the human gut turns out to be far more than a digestive footnote — it may be a central orchestrator of how…
Autophagy within hypothalamic NPY+/AGRP+ neurons governs hippocampal presynaptic active zone architecture and proteostasis through non-cell autonomous…
Analysis of three waves of the English Longitudinal Study of Ageing—covering 8,389 (2004/05), 8,549 (2012/13), and 6,090 (2023/24) community-dwelling adults…
What if the Western immune system — shaped by decades of antimicrobial environments, processed diets, and low pathogen exposure — is actually less equipped to…
The longstanding assumption that surviving an infection depends almost entirely on killing pathogens faster than they kill you is being quietly dismantled. A…
Two neuromuscular diseases with overlapping immune-mediated mechanisms can have strikingly opposite effects on lifespan — and a large death-certificate…
Lifelong restriction of valine — one of three branched-chain amino acids (BCAAs) — in C57BL/6J mice produced a 23% increase in median male lifespan, alongside…