Found 1276 results for "longevity"
Identifying reliable tissue-level markers of biological aging has long been a bottleneck for both clinical assessment and longevity research. A structural…
For anyone banking on epigenetic clocks to guide longevity interventions, this investigation lands as a serious reality check. The question it answers is…
Analyzing weekly all-cause mortality data from 31 European countries (2015 onward, COVID-19 period excluded from baseline), NeMMo — an evolution of the…
Pooling data from 11 Indian studies covering 3,512 children and adolescents under 18, this meta-analysis estimates an overall NAFLD prevalence of 35.4% (95%…
Treating 12-month-old female mice carrying the APOE4 Alzheimer's risk allele with 14.4ppm 17α-estradiol (17αE2) for six months reduced adiposity and improved…
Applying directed evolution to the Drosophila gut microbiome outside the host generated a paraquat-resistant (PQR) microbial community that, when transplanted…
For decades, adipose tissue was dismissed as passive energy storage, but mounting evidence positions it as a master regulator of systemic aging. A newly…
One of the most vexing problems in longevity medicine is that the same cellular arrest mechanism that protects against cancer — senescence — also generates a…
One in eight people worldwide now lives with a diagnosable mental disorder, and the cumulative toll on healthy years of life has grown substantially over…
Psoriasis patients (n=20) showed significantly accelerated epigenetic aging compared to matched controls across four mortality-predictive DNA methylation…
Understanding how cells shuttle glycerol across their membranes may matter far more than it first appears. Glycerol is not merely a byproduct of fat breakdown…
For decades, the cancer vaccine field carried a reputation for overpromising and underdelivering — Sipuleucel-T's 2010 approval stood as both a milestone and…
A diabetes drug taken by hundreds of millions of people worldwide may be quietly doing something far more profound than regulating blood sugar — and the…
For the millions of adults managing knee osteoarthritis, intra-articular corticosteroid injections have become a go-to bridge between failed oral pain relief…
Blood cancers driven by clonal stem cell mutations occupy a unique space in oncology — they evolve slowly, often over decades, yet carry serious risks of…
Every time a cell's DNA suffers a double-strand break — one of the most catastrophic forms of genetic damage — it must orchestrate a precise molecular repair…
Most genomic research can tell us which genes move together — but not which ones actually drive the others. That distinction matters enormously for drug…
One of evolutionary biology's most contested ideas — that boldness, longevity, and fertility are biologically yoked together rather than independently tunable…
Age-related macular degeneration remains one of the leading causes of irreversible vision loss in older adults, and oxidative damage to the eye's delicate…
Falls remain one of the leading causes of injury-related death and disability in adults over 65, yet decades of prevention campaigns have barely moved the…