Studies
Transdermal Estradiol Patches Show Potential Role in Prostate Cancer Treatment
Hormone manipulation has long been the cornerstone of advanced prostate cancer management, but the cardiovascular toll…
Studies
Sex Hormones Shape Cardiovascular Risk Through Distinct Biological Pathways
Cardiovascular disease remains the leading cause of death globally, yet the biological mechanisms through which sex…
Studies
Tumor Acidity Hijacks PARP1 Acetylation to Escape Ovarian Cancer Treatment
For the hundreds of thousands of women diagnosed annually with epithelial ovarian cancer, PARP inhibitors represent a…
Studies
NEJM Correspondence Revisits LDL Targeting Strategy Evidence in Cardiovascular Care
Few questions in preventive cardiology carry more practical weight than how aggressively to lower LDL cholesterol…
Studies
Targeted NaV1.8 Ion Channel Blockade Shows Efficacy in Phase 2b Acute Pain Trial
Acute pain management stands at a crossroads: opioids remain the dominant treatment despite their addiction liability…
Studies
Prenatal DDT Exposure Linked to 3.7-Fold Higher Breast Cancer Risk
The window of greatest vulnerability to chemical carcinogens may begin before birth — a finding that fundamentally…
Studies
Chemotherapy Triggers Fructose Secretion That Fuels Ovarian Cancer Spread
One of oncology's most troubling paradoxes is that the treatments designed to kill cancer may simultaneously create…
Studies
Primary Aldosteronism: Underdiagnosed Hypertension Cause With Distinct Cardiovascular Risk
Hypertension affects roughly one in three adults globally, yet a significant hormonal driver hiding beneath the…
Wellbeing
Agentic AI Systems Proposed to Scale Specialist Dementia Diagnosis Globally
The global shortfall of dementia specialists represents one of the most urgent bottlenecks in neurodegenerative care…
Wellbeing
Three-Month Yoga Protocol Shifts Autonomic Balance in IBS Patients
Irritable bowel syndrome sits at a frustrating intersection of physical and neurological dysfunction, and for the…
Studies
Five Blood Proteins Predict Fatty Liver Disease 16 Years Before Diagnosis
Silent, slow-moving liver disease rarely announces itself until significant damage is done — which is precisely why a…
Longevity
CHIP Mutations and Inflammaging Form a Self-Reinforcing Loop Driving Age-Related Disease
For decades, chronic low-grade inflammation in older adults was treated as a background condition — an inevitable…
Studies
16-Year-Ahead Blood Protein Signature Detects Silent Liver Disease Risk
Liver disease rarely announces itself early — by the time metabolic dysfunction-associated steatotic liver disease…
Studies
ML-Derived LDL Equation Rivals Gold Standard Across Extreme Cholesterol Ranges
Accurate LDL cholesterol estimation underpins one of medicine's most consequential clinical decisions — whether and…
Studies
PSMA-Targeted Nanoprobe Combines MRI Contrast and Chemoradiotherapy Activation in Prostate Cancer
Locally advanced prostate cancer poses a stubborn clinical challenge: tumors that spread diffusely within and beyond…
Wellbeing
Single Psilocybin Dose Cuts Veteran Anxiety 59% Through 12 Months
For veterans carrying the compounded burden of treatment-resistant depression and PTSD, standard pharmacotherapy often…
PREPRINTWellbeing
AI Algorithm Matches Researcher-Tuned Spinal Stimulation for Blood Pressure Control in SCI
An automated algorithm for cardiovascular spinal cord epidural stimulation (CV-scES) achieved a mean correlation…
PREPRINTStudies
Compact ABPM Device Cuts Pain Scores by 70% vs Traditional Monitor in Crossover Trial
In a pilot randomized crossover study of 20 adults in New York City, the compact cuff-integrated SOMNOmedics ABPM Pro…
PREPRINTLongevity
Elevated MLR (>0.63) Associated with All-Cause Mortality Risk in Systematic Review of 18,631 CKD Patients
Across 11 observational studies enrolling 18,631 individuals with chronic kidney disease (CKD)—ranging from…
PREPRINTLongevity
PRRC2B RNA-Binding Protein Loss Triggers Patent Ductus Arteriosus via Smooth Muscle Translational Failure
Complete genetic knockout of PRRC2B — an RNA-binding protein governing uORF-dependent and independent translation…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.