Midlife Exercise Linked to 20% Fewer Memory Complaints Three Decades Later
Among 4,397 women in the NYU Women's Health Study (mean age 46 at baseline, 79 at follow-up), those in the top tertile of midlife physical activity had 20%…
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Among 4,397 women in the NYU Women's Health Study (mean age 46 at baseline, 79 at follow-up), those in the top tertile of midlife physical activity had 20%…
In a 12-month unpredictable chronic mild stress model in mice, chronic stress amplified systemic inflammation, damaged multiple tissues and shortened…
Across three cohorts totaling 12,042 patients with chronic kidney disease, higher resting heart rate (RHR) predicted greater all-cause and cardiovascular…
Across 16 years of follow-up in 324,284 UK Biobank adults aged 40-65, 2,674 hip fractures occurred. Middle quintiles of leisure-time activity carried the…
In mice made diabetic with a high-fat diet plus streptozotocin, low- and high-dose D-psicose (a rare sugar) improved serum lipids, lowered ALT and AST…
In patients with severe obesity undergoing two-stage bariatric surgery, picrosirius-red-measured pericellular fibrosis in abdominal fat showed no baseline…
A Bayesian network meta-analysis of 43 randomized controlled trials (2,433 participants) systematically compared lifestyle interventions for cardiometabolic…
Among 10,462 UK Biobank participants who later developed cancer, higher cardiorespiratory fitness (CRF) at baseline was associated with dramatically lower…
The bone-derived hormone osteocalcin (OCN) acts on spinal motoneurons via the receptor GPR158 to regulate autophagy, mitophagy, and mitochondrial activity…
In aging Drosophila brains, octopamine (the invertebrate equivalent of noradrenaline) normally drives glucose uptake in astrocytes and lactate shuttling to…
Pooling 13 randomized controlled trials, exercise interventions produced a statistically robust improvement in balance function among people with osteoporosis…
In three genetically distinct BXD mouse strains fed a 60% fat diet for 32 weeks, voluntary wheel running (~5 km/day sustained) improved oral glucose tolerance…
In the largest exercise-testing cohort to date — 562,234 adults followed for a mean 10.2 years — each additional MET of peak cardiorespiratory fitness (CRF)…
In a secondary analysis of the landmark FINGER randomized controlled trial (N=1,260 at-risk older adults), six core Alzheimer's disease plasma biomarkers…
Cardiovascular disease rarely announces itself — it builds silently over decades, starting with metabolic dysfunction that quietly hardens arteries long…
Among 92 adults over age 50 living with HIV (PWH), those receiving automated tailored text messages matched to daily reported exercise barriers — combined…
In a secondary analysis of the SPARX Phase 2 randomized clinical trial (128 de novo Parkinson's disease patients), sedentary time significantly modified…
A systematic review and meta-analysis of seven randomized controlled trials (314 participants) found that combining bisphosphonates with structured physical…
Exposing cultured human non-small cell lung cancer cells to post-exercise serum from master athletes — representing lifelong high physical activity…
Among 171 adults tracked with wearables over seven baseline nights and seven nights on a temperature-controlled sleep surface (Orion Sleep System)…