Researchers analyzed pulse-wave patterns in 101 Taiwanese older adults during cognitive tasks, finding that those with mild cognitive impairment (MCI) showed fragmented cardiovascular responses compared to cognitively intact participants. The study measured Harmonic Response Consistency Scores, revealing that healthy adults exhibited coordinated cardiovascular down-modulation during mental challenges, while MCI participants showed disorganized responses with significantly lower consistency scores. This cardiovascular-cognitive disconnect represents an intriguing window into early neurodegeneration. The findings align with emerging evidence that vascular health and cognitive function are intimately linked, with cardiovascular dysregulation potentially preceding or accelerating cognitive decline. For aging adults, this suggests that monitoring heart rhythm responses to mental stress could complement traditional cognitive assessments. However, this community-based observational study has notable limitations: the small reference group (n=12), cross-sectional design preventing causal inference, and geographic specificity. As a preprint awaiting peer review, these results require validation in larger, diverse populations before clinical application. The approach represents an incremental advance in non-invasive screening methods, though its practical implementation would require specialized equipment and standardized protocols.