Longevity
Myelin-Producing Brain Cells Identified as Active Drivers of Age-Related Cognitive Decline
For decades, cognitive aging research has centered on neurons and amyloid plaques, but mounting evidence suggests the…
Wellbeing
Adolescent Mental Health ED Visits Reduced 25%, Admissions 58% in Primary Care QI Initiative
Adolescent mental health crises are landing teenagers in emergency departments at alarming rates, an outcome widely…
Longevity
Brain Cell Senescence Spreads Via SASP Signals: Key Targets Identified
Cellular aging in the brain may not be an isolated event confined to individual neurons or glia — it appears to be…
Longevity
Gut Bacterium and Its Metabolite Shown to Counter Age-Driven Inflammation
Chronic low-grade inflammation — now widely termed inflammaging — is increasingly recognized as a central driver of…
Studies
OCD Polygenic Scores Over-Transmitted in Body-Focused Repetitive Behavior Families
For the millions of people who pull their hair or pick their skin compulsively, the question of whether these…
Longevity
Stress Neuropeptide CRF Links Mitochondrial Damage to Accelerated Cellular Aging
Chronic psychological stress has long been suspected to accelerate biological aging, but the molecular machinery…
Longevity
Sex-Stratified Biological Clocks Reveal Divergent Aging Transitions in Men and Women
The assumption that aging unfolds similarly in men and women has quietly shaped decades of longevity research — and it…
Longevity
APOE ε2 Siblings Aged 94–105 Show Unexpected Cognitive and Brain Resilience
For the roughly 7% of the population carrying at least one APOE ε2 allele, this report offers a striking window into…
Studies
Annual mRNA-1273 Dose Shows $23,265 Cost Per QALY Gained in US Model
For health systems and policymakers weighing the ongoing value of COVID-19 vaccination, economic modeling that…
Longevity
cGAS Deletion Triggers LINE1 Retrotransposon Escape, Accelerating Mouse Aging
A fundamental assumption in aging biology has long been that genomic instability and chronic inflammation arise…
Studies
IPV Associated with Female HIV Burden as Funding Cuts Risk 2030 Reversal
Three decades of hard-won progress against HIV may be approaching an inflection point — not because the science has…
PREPRINTStudies
Systolic Blood Pressure—Not BMI—Drives Cholecystitis Risk at High Altitude
Among 605 patients undergoing laparoscopic cholecystectomy at a Qinghai hospital situated at 2,260 meters elevation…
PREPRINTStudies
T2D Subtype SIDD Carries 3.87× Higher Cancer Hazard Than Non-Diabetics
Among 575,139 newly diagnosed Type 2 diabetes patients matched against 689,719 non-diabetic adults in the Epic Cosmos…
PREPRINTStudies
Long COVID Raises Re-Infection Risk 21%, Triples Symptom Recurrence After Second Infection
Among 1,543 participants in the Arizona CoVHORT six-year longitudinal study, 700 reported Long COVID (LC) symptoms…
Studies
Global TB Burden Mapped Across 204 Nations: MDR Strains and HIV Complicate Progress
Tuberculosis remains one of the most consequential infectious disease challenges of the modern era, and a…
Nutrition
High-Quality Diet Linked to Slower Lung Function Decline in COPD Patients
For the roughly 300 million people worldwide living with COPD — a disease defined by irreversible airflow obstruction…
Wellbeing
Urban Woodland Improvements Near Homes Show No Mental Health Benefit in Large Scottish Cohort
The assumption that greening urban spaces automatically translates into measurable mental health gains for nearby…
Studies
EAACI Pollen Guidelines Recommend Real-Time Forecasts and Monitoring for Pollen-Triggered Asthma and Rhinitis
For the estimated 400 million people worldwide living with allergic rhinitis and the hundreds of millions managing…
Longevity
Aurora Kinase Inhibition Converts Melanoma Senescence Into Immune Attack Signal
The assumption that therapy-induced cellular senescence is merely a side effect to be tolerated is being fundamentally…
Nutrition
Mulberry Compounds Reshape Gut Microbiome via Processing-Dependent Mechanisms
For those tracking functional foods with genuine microbiome impact, mulberry deserves more attention than it typically…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.