Studies
APRIL Antibody Reduces Kidney Disease Progression by 38% in IgA Nephropathy
The monoclonal antibody sibeprenlimab, which targets the APRIL protein involved in antibody production, demonstrated a…
Studies
Atacicept Reduces Kidney Disease Progression by 42% in IgA Nephropathy
Atacicept, a B-cell targeting biologic, demonstrated a 42% reduction in kidney function decline among patients with IgA…
Studies
Combined HER2 Inhibitors Show Superior Survival in Advanced Breast Cancer
The dual-drug approach combining trastuzumab deruxtecan with pertuzumab demonstrated enhanced progression-free survival…
Studies
Delayed Cardiac Intervention Matches Immediate Treatment for Heart Attack Survival
Cardiac intervention timing during acute myocardial infarction may be more flexible than previously assumed, with defer…
Studies
TAVR Procedure Extends Survival in Low-Risk Aortic Stenosis Patients
Transcatheter aortic valve replacement (TAVR) demonstrated sustained mortality reduction and improved cardiovascular ou…
Studies
Enzalutamide Extends Survival in Early Prostate Cancer Recurrence
Enzalutamide, an androgen receptor inhibitor, demonstrated significant survival benefits in men with biochemically recu…
Studies
OTOF Gene Therapy Enables Hearing Recovery in Hereditary Deafness Cases
Clinical trials demonstrate that direct OTOF gene delivery via adeno-associated virus vectors can restore functional he…
Longevity
Gratitude Practice Linked to Measurable Longevity Biomarkers
Regular gratitude practices activate measurable physiological pathways associated with extended healthspan, according t…
Research
NIH releases Alzheimer’s Disease and Related Dementias Research Progress Report and FY27 Professional Judgment Budget
The National Institutes of Health (NIH) has released two key documents related to Alzheimer's disease and related demen…
Research
Connect with NIA at AAIC 2025
The National Institute on Aging (NIA) will be present at the Alzheimer's Association International Conference (AAIC) in…
Longevity
Dehydration Accelerates Aging and Mortality Risk in Adults
Chronic mild dehydration appears to function as an accelerant for biological aging processes, with serum sodium levels…
Research
Research training spotlight: NIA funding enables researcher-mentor to “pay it forward”
The article highlights how NIA funding has enabled renowned researcher María J. Marquine, Ph.D. to mentor other researc…
Research
NIA-funded small business spotlight: Bone Health Technologies shakes up the market to prevent bone density loss
The article highlights Bone Health Technologies, an NIA-funded small business that has developed innovative solutions t…
Research
NIA Experimental Aging Research Training Course
The National Institute on Aging (NIA) is offering an annual summer training course in experimental aging research from…
Longevity
Scientists Propose Cellular Replacement Framework for Extending Human Healthspan
A consortium of aging researchers has advanced a unified theoretical framework positioning cellular and molecular repla…
Longevity
Blood Biomarker Clock Accurately Predicts Mouse Lifespan and Frailty
National Institute on Aging researchers developed a biological aging clock using blood biomarkers that successfully pre…
Longevity
UK Biobank Database Enables Large-Scale Human Longevity Research
The UK Biobank represents a transformative resource containing genetic, lifestyle, and health data from over 500,000 pa…
Studies
Plexin-B1 Gene Regulates Amyloid Plaque Architecture and Microglia Response
Plexin-B1, a gene traditionally known for guiding axon growth during neural development, actively shapes the glial cell…
Studies
Synaptic Protection Drug Demonstrates Safety Profile in Alzheimer's Patients
An experimental therapeutic designed to enhance synaptic resilience has cleared initial safety hurdles in Alzheimer's p…
Wellbeing
Monthly Cash Payments Preserve Memory Function in Aging Adults
Monthly cash payments of approximately $20 preserved cognitive function and reduced dementia risk among adults aged 40-…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.