Supplements
High-Dose DHA Crosses Blood-Brain Barrier in At-Risk Adults, APOE Status Irrelevant
For the millions of adults carrying the APOE ε4 gene variant — the single largest genetic risk factor for Alzheimer's…
Studies
Dual Adjuvant Therapy Cuts Kidney Cancer Recurrence Risk by 28%
For the roughly 400,000 people diagnosed globally each year with kidney cancer, the post-surgical window represents…
Fitness
16-Week Exercise Cuts HIV-Related Frailty 37% in Adults Over 50
Among 94 older adults with HIV who completed a 16-week randomized exercise trial, pre-frailty and frailty prevalence…
Longevity
Review Proposes Four Aging Hallmarks Form Self-Reinforcing Network in AMD, Glaucoma, Diabetic Retinopathy
Four molecular hallmarks — mitochondrial dysfunction, loss of proteostasis, cellular senescence, and epigenetic drift…
Studies
TBI in Older Veterans Reveals Bidirectional Links to Dementia, Stroke, Parkinson's
The conventional view of traumatic brain injury as a trigger for neurological decline may be only half the story. For…
Studies
40% of UK Emergency Admissions Could Be Managed as Same-Day Outpatient Care
For health systems straining under the weight of aging populations, the question of which hospital admissions are…
Studies
Letrozole Upgrades Sperm Concentration in 3-Month Trial of Severe Male Infertility
Male infertility affects roughly one in six couples worldwide, yet evidence-based treatments for the most severe forms…
Studies
Visible Light Rewires Immune Cells Against Tumors Through Melanopsin Epigenetics
The idea that ordinary visible light could reshape the immune system's cancer-fighting capacity sounds…
Longevity
Aging Muscle Exports miR-125a-5p Vesicles That Silence Bone Formation
The long-held assumption that sarcopenia and osteoporosis simply co-occur with age may need revision. New mechanistic…
Studies
RNA m6A Methylation Writers Emerge as Targets for Autoimmune Disease Therapy
A largely invisible layer of gene regulation — not the DNA sequence itself but chemical tags on RNA — may hold the key…
Studies
RNA Methylation Activates Triple-Death Pathway in Sepsis Heart Damage
Understanding why the heart fails during severe infection has long eluded critical care medicine. A newly identified…
Longevity
Centenarian Gene Variant Linked to Platelet CD47 Changes Associated with Suppressed Aging-Related Inflammation
Understanding why some people reach 100 in robust health while others decline decades earlier is one of longevity…
Studies
Upadacitinib Outperforms TNF Inhibitors in Real-World RA Treatment Persistence
For the roughly 1.3 million Americans living with rheumatoid arthritis, choosing between newer JAK inhibitors and…
Studies
Pain-Sensing Nerves Suppress Anti-Tumor Immunity in Lung Cancer Via CGRP
Most cancer immunology research focuses on T cells, checkpoint inhibitors, and tumor mutational burden — but the…
Studies
Germline-Targeting HIV Vaccine Elicits Broad Neutralizing Antibodies in Primates
For four decades, HIV's extraordinary ability to mutate and diversify has defeated every conventional vaccine…
Studies
Pediatric Sleep Medication Use in Japan Doubled Over Ten Years
Children and adolescents sleeping poorly enough to require prescription medication represents a quiet public health…
Longevity
Two Neural Circuits Control Muscle Autophagy via Calcium and TGF-β Signaling
Understanding how the nervous system remotely governs cellular housekeeping in distant tissues could reshape how we…
Studies
Oral Paltusotine Outperforms Rival Acromegaly Drugs on Tolerability and Control
For the estimated 60,000 Americans living with acromegaly — a condition of chronic growth hormone excess that…
Studies
Copper Overload Triggers Mitochondrial Self-Destruction Via Lipoylated Enzyme Aggregation
A largely overlooked fact about copper is that at supraphysiological concentrations it doesn't merely impair cells…
Studies
Brush Biopsies Detect Hidden TP53 Mutations in Clinically Normal Oral Tissue
For the millions at elevated risk of head and neck cancer — including those with inherited DNA-repair deficiencies…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.