Nutrition
8-Hour Feeding Window Extends Male Mouse Lifespan 12%, Sex Differences Emerge
For anyone practicing intermittent fasting, the assumption has been that eating within a compressed daily window…
Longevity
Post-Menopausal Ovary Becomes Active Immune Organ, Influencing Whole-Body Aging
For decades, the ovary after menopause was considered a spent organ—biologically silent once its follicles were gone…
Studies
Seven DLBCL Proteogenotypes Reveal Hidden High-Risk Subtype Beyond Standard Markers
For patients diagnosed with diffuse large B cell lymphoma, standard molecular classification still leaves a…
Studies
Unacylated Ghrelin Preserves 70% Muscle Force in Cancer Cachexia Model
For the millions of cancer patients who lose dangerous amounts of muscle mass during treatment, cachexia represents…
Studies
Six-Month Stewardship Program Targets Drug-Resistant Bacteria Across Vietnamese Hospitals
Antibiotic resistance quietly reshaping hospital safety worldwide rarely receives the granular, pre-and-post…
Studies
14-Protein Blood Signature Predicts Lung Cancer Five Years Before Diagnosis
Early cancer interception—stopping a tumor before it becomes one—has long been hampered by the inability to identify…
Nutrition
Plant-Based Diets Linked to 5–7% Lower MACE Risk in 99,000-Person CKM Cohort Study
Across 99,064 participants drawn from the UK Biobank and NHANES (2005–2018), adherence to the Alternative…
Longevity
Stress Ages Blood Stem Cells Via Brain-Gut-Spermidine-Ferroptosis Cascade
Chronic psychological stress impairs hematopoietic stem cell (HSC) self-renewal and lymphoid differentiation by…
Longevity
PRMT Enzymes Act as Molecular Rheostats Governing Muscle-Aging Degeneration
Protein arginine methyltransferases (PRMTs) function as molecular rheostats that tip mitochondrial stress responses in…
Longevity
Rapamycin Reverses Brain Vascular Amyloid, Hemorrhage, and Memory Loss in AD Mice
In Tg2576 mice modeling Alzheimer's disease with cerebral amyloid angiopathy (CAA), mTOR hyperactivation drives…
Longevity
8-Week Multimodal Trial Tests Gerotype-Personalized NMN, Urolithin A & Ergothioneine Stack
The PROMETHEUS feasibility trial enrolls 20 middle-aged-to-older adults in an 8-week multimodal intervention…
Studies
Depression Associated With 57% Higher Alzheimer's Conversion Risk in MCI: Meta-Analysis of 17 Studies
For the estimated 15–20% of older adults living with mild cognitive impairment, the question of who progresses to…
Studies
Global Mental Disorder Burden Mapped Across 204 Nations Over Three Decades
Mental health conditions collectively represent one of the largest sources of disability-adjusted life lost worldwide…
Longevity
Geroscience Gains Standardized Immune Aging Biomarker Framework for Clinical Trials
Every anti-aging intervention trial faces the same problem: how do you measure whether a treatment is actually slowing…
Studies
Pan-Cancer AI Model Predicts Immunotherapy Response From Tumor Gene Expression
Knowing in advance whether a patient will respond to immunotherapy could spare them months of ineffective treatment…
Studies
First Lassa Fever Treatment Trial in Decades Advances Vaccine Pipeline
For the roughly 300,000 people infected annually with Lassa virus across West Africa — and the travelers, healthcare…
Studies
Endocrine-Disrupting Chemicals May Amplify Cardiovascular Risk in Cancer Patients
For the millions of adults navigating cancer treatment, cardiovascular complications are already a leading cause of…
Fitness
Lifelong Exercise Cuts Muscle Aging Markers by Half at Molecular Level
Most people accept muscle decline as an inevitable feature of aging, but new molecular evidence suggests that…
Longevity
Damage Production Rate, Not Repair Capacity, Governs Lifespan Across Species
Understanding why humans live decades while fruit flies live weeks has challenged biologists for generations. A new…
Studies
Brain-Penetrant Molecule Targets TDP-43 Core Region, Extends ALS Mouse Survival
For the roughly 30,000 Americans living with ALS at any given time, disease-modifying options remain desperately…
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Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.