PREPRINTNutrition
DASH Diet From Midlife Onward Cuts Dementia-Linked Brain Damage by 12%
In 892 older Singaporean adults tracked across 32 years (1993–2025), higher adherence to the DASH diet during midlife…
PREPRINTWellbeing
Pre-Existing Depression and Anxiety Double Post-COVID Risk; Brain Structure Irrelevant
In 8,464 SARS-CoV-2-infected participants from the German National Cohort (NAKO), pre-infection mental health…
PREPRINTFitness
Tailored SMS + Motivational Interviewing Sustains Exercise in Over-50s with HIV
Among 92 adults over age 50 living with HIV (PWH), those receiving automated tailored text messages matched to daily…
PREPRINTStudies
Diabetes Drugs Show No Clear Genetic Link to Vascular Dementia Prevention
Applying two-sample drug-target Mendelian randomisation (MR) across eight antidiabetic drug targets, this analysis…
PREPRINTFitness
Sedentary Time Blunts VO2max Gains from Moderate Exercise in Parkinson's Patients
In a secondary analysis of the SPARX Phase 2 randomized clinical trial (128 de novo Parkinson's disease patients)…
Studies
Ad-DiaRem Score Best Predicts Type 2 Diabetes Remission After Bariatric Surgery
In a Malaysian cohort of 204 adults with type 2 diabetes undergoing bariatric surgery (85% sleeve gastrectomy, 15%…
PREPRINTSupplements
Multi-ingredient NAD+ supplement raises blood NAD+ by 74% in 28 days
A 28-day double-blind, placebo-controlled pilot trial found that Qualia NAD+, a multi-ingredient nutraceutical…
PREPRINTSupplements
NAD+ Supplement Raises Blood Levels 67% in 28-Day Placebo-Controlled Trial
A 28-day double-blind, placebo-controlled trial of Qualia NAD+, a multi-ingredient supplement combining nicotinamide…
PREPRINTWellbeing
Daily Negative Mood Predicts 60% Higher Heart Attack Recurrence Risk
Among 287 midlife adults (mean age 51, 43% women) monitored within 8 months of a myocardial infarction, each standard…
PREPRINTStudies
NLR Beats SII and PLR for CV Mortality; None Add Much to Standard Risk Models
Across two independent NHANES cohorts totalling 30,533 US adults followed for up to 11.4 years, the…
PREPRINTWellbeing
18-Month Meditation Trial Shows Minimal Sleep Benefits in Healthy Older Adults
An 18-month structured meditation intervention in 120 cognitively unimpaired adults aged 65 or older produced only one…
Longevity
Direct AMPK Activator Compound 991 Extends Lifespan Across Three Species
Direct activation of AMP-activated protein kinase (AMPK) using compound 991 — a small molecule that binds AMPK…
Supplements
Dasatinib + Quercetin Clears Senescent Cells, Reverses Liver Fibrosis in 47% of Patients
A phase-2 double-blind RCT of 31 participants with fibrotic metabolic dysfunction-associated steatohepatitis (MASH)…
Studies
SGLT2 Inhibitors Cut BP and Weight in Diabetic CKD but Miss Renal Markers
Across 17 randomized controlled trials enrolling 29,192 patients with diabetic chronic kidney disease, SGLT2…
Studies
Daily E-Cigarette Use Linked to 14.6x Higher Odds of Quitting Among Never-Planners
Among U.S. adults who smoked daily and explicitly never planned to quit, those who took up daily e-cigarette use were…
Fitness
Exercise Plus Bisphosphonates Boosts Femoral Bone Density and Quality of Life
A systematic review and meta-analysis of seven randomized controlled trials (314 participants) found that combining…
Supplements
Crocin (saffron pigment) reverses fatty liver markers in rats on high-fat diet
In 42 male Wistar rats fed a high-fat diet for eight weeks to induce NAFLD, intraperitoneal crocin administered over…
Longevity
High Cardiovascular Health Score Adds 5-10 Years of Disease-Free Life
Across 130,837 adults in two large prospective cohorts — UK Biobank and NHANES — scoring in the top tier of the Life's…
Fitness
Lifelong Exercise Primes Lung Cancer Cells to Respond Better to Cisplatin
Exposing cultured human non-small cell lung cancer cells to post-exercise serum from master athletes — representing…
Nutrition
Food Pantry 'Food is Medicine' RCT Achieves 81% Retention, Improves Diet Quality
A three-arm pilot RCT of 210 low-income patients in a Dallas safety-net healthcare system found that a Food is…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.