PREPRINTNutrition
Processed-Meat/Fried-Food Pattern at Age 3 Raises Asthma Odds 42–59%
A data-driven principal component analysis of age-3 food-frequency questionnaires from the Vitamin D Antenatal Asthma…
PREPRINTLongevity
Transformer AI Hits 0.821 AUC Predicting 10-Year CVD Risk in 180,000 Adults
A Transformer-based deep learning model trained on 100,056 Japanese adults without baseline cardiovascular disease…
PREPRINTNutrition
Global Diet Shift Could Cut 4.28 Gt CO₂/yr While Reducing Inflammation Simultaneously
A supply-side dietary optimization across 182 countries found that anti-inflammatory eating patterns and low-carbon…
PREPRINTLongevity
EAT Density Beats BMI: 95th Percentile Flags 70% Higher MI/Death Risk
In a retrospective multicenter analysis of 42,842 patients undergoing myocardial perfusion imaging, age- and…
Longevity
Sarcopenia's Root Cause Debate: Motor Neurons vs. Muscle Fibers as Therapeutic Targets
A perspective from the University of Basel challenges the dominant therapeutic paradigm for sarcopenia — the…
Studies
Tirzepatide Hits -19%, Retatrutide -22%: GLP-1 Weight Loss Hierarchy Mapped Across 38 RCTs
Across 38 randomized controlled trials enrolling 25,816 adults with overweight or obesity but without diabetes…
Longevity
Brain Perivascular Spaces Reveal Heritable Microvascular Signature Linked to Depression and Cortisol
In a family-based cohort of 1,050 adults (mean age 59.3 years), brain perivascular space (PVS) morphometry…
Supplements
Curcumin and Sulforaphane Activate Nrf2 Pathway, Improving Schizophrenia Symptoms in 953-Patient Meta-Analysis
Across 16 randomized controlled trials encompassing 953 patients (mean age 35.27 years), Nrf2-activating compounds…
Longevity
SLC1A5 Glutamine Transport Controls Macrophage Senescence and Liver Regeneration via Gas6
A newly identified immunometabolic axis—SLC1A5→glutamine→senescence→Gas6→efferocytosis—governs how macrophages…
Studies
COVID Learning Gaps Persisted Nine Years in Ghanaian Children, Study Finds
For the millions of children who experienced pandemic-era school closures, the educational damage may run far deeper…
Studies
Clinical Guidance Issued on E-Cigarettes as Smoking Cessation Tools
Quitting combustible cigarettes remains one of the highest-impact health decisions an adult smoker can make, yet…
Studies
SGLT2 Inhibitor Dapagliflozin Fails to Cut Post-Cardiac Surgery Kidney Injury Risk
Protecting the kidneys during and after cardiac surgery remains one of the most stubborn unsolved problems in…
Studies
Dapagliflozin Before Cardiac Surgery Cuts Acute Kidney Injury Risk
Acute kidney injury following cardiac surgery is one of the most feared postoperative complications, affecting up to…
Wellbeing
AI Scribes Show Mixed Results on Clinician Time and Visit Volume
Clinician burnout driven by documentation burden remains one of medicine's most stubborn systemic problems, making any…
Studies
E-Cigarettes as Cessation Tools: Why Physician Guidance Remains Fractured
For the roughly 28 million adults in the United States who still smoke, the gap between what physicians know, what…
Studies
Dapagliflozin Cuts Cardiac Surgery AKI Risk in Randomized Trial
Acute kidney injury following cardiac surgery remains one of the most feared postoperative complications, affecting up…
Studies
High-Dose Vitamin D3 Extends Progression-Free Survival in Metastatic Colorectal Cancer Trial
Vitamin D's role in cancer biology has long been theorized but frustratingly difficult to confirm in rigorous clinical…
Studies
Clinicians Need New Standards for Interpreting AI-Wearable Physiologic Data
As wearable devices become ubiquitous health monitors, the flood of continuous physiologic data they generate is…
Studies
High-Dose Vitamin D3 Extends Progression-Free Survival in Metastatic Colorectal Cancer Trial
For patients facing metastatic colorectal cancer — one of the deadliest and most treatment-resistant malignancies…
Studies
Thrombectomy Extends Functional Recovery Gains to One Year in Large-Core Strokes
For stroke survivors with the most severe brain injuries, the question of whether aggressive intervention pays off…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.