PREPRINTStudies
ECG Data Adds Marginal 10-Year Heart Risk Prediction Beyond Standard Factors
Analysis of 41,076 UK Biobank participants found that ECG measurements taken during rest, exercise, and recovery indepe…
PREPRINTStudies
Six Distinct Pathways to Metabolic Syndrome Identified in Japanese Men
Hierarchical clustering analysis of 592 Japanese men aged 49-64 identified six distinct pathways leading to metabolic s…
PREPRINTLongevity
Diabetes Associated with 0.76 SD Faster Biological Aging, Mediating 88.5% of Cognitive Decline
Analysis of 2,384 older U.S. adults reveals diabetes accelerates biological aging by 0.76 standard deviations using the…
PREPRINTWellbeing
Aldosterone levels predict 4% higher hypertension odds per ng/dL in postmenopausal women
Each 1 ng/dL increase in aldosterone corresponded to 4% higher odds of hypertension in 999 postmenopausal women aged 66…
PREPRINTStudies
COVID-19 Modeling Reveals How Social Inequality Drives Pandemic Deaths
A comprehensive geospatial epidemic model analyzing Brazil's COVID-19 pandemic demonstrates that pre-existing social in…
PREPRINTLongevity
Brain Volume Peaks at Glucose 4.4-4.7 mmol/L, Sex Differences Found
Analysis of 36,321 UK Biobank participants reveals an inverted J-shaped relationship between blood glucose levels and b…
PREPRINTLongevity
Blood Immune Signatures Predict Arterial Thickening Over 18 Years
Analysis of 148 participants in the Barilla Offspring Study revealed that specific gene expression patterns in peripher…
PREPRINTWellbeing
Vaping Linked to 82% Higher Risk of Heart Rhythm Abnormalities in Adolescents and Young Adults: Study
Analysis of 114,404 adolescents and young adults (ages 11-24) reveals vaping increases heart rhythm abnormality risk by…
PREPRINTStudies
Cerebral Protection Devices Linked to 66% Lower TAVR Stroke Risk in 1,101 Patients
Cerebral embolic protection devices reduced ischemic stroke incidence from 4.1% to 1.4% in patients undergoing transcat…
PREPRINTLongevity
High Calcium-Phosphate Product Associated With 43% Higher Post-Stent Death Risk in CKD
Chronic kidney disease patients with elevated calcium-phosphate product (CPP) — a biomarker reflecting disrupted minera…
Studies
Four in Ten Global Cancers Linked to Preventable Risk Factors
A sweeping analysis of cancer patterns across 185 countries reveals that prevention strategies could theoretically elim…
Longevity
Accelerating Epigenetic Clock Changes Independently Predict Mortality Risk
The rate at which your biological age advances may matter more than your current biological age when predicting longevi…
Wellbeing
Sleep Misperception Disorder Resists Multiple Drug Treatments in Complex Case
Sleep disorders can manifest in ways that challenge our understanding of the relationship between objective sleep quali…
Studies
Romiplostim Enables 84% of Cancer Patients to Maintain Full Chemotherapy Dosing
Cancer patients face a cruel trade-off: the chemotherapy needed to fight their disease often destroys platelets, forcin…
Studies
3D Cancer Organoids Reveal GPC3-CAR T Cell Efficacy Against Head Neck Tumors
Precision immunotherapy for head and neck cancers could gain significant momentum from a breakthrough laboratory platfo…
Studies
Multi-Omics Biomarkers Could Transform Prostate Cancer Precision Medicine
The persistent challenge of prostate cancer overdiagnosis affects millions of men who undergo unnecessary treatment for…
Wellbeing
Widowed Men Face Higher Mortality Risk Than Women After Spousal Loss
The stark reality that men and women navigate grief fundamentally differently has profound implications for how familie…
Studies
Alternative Pancreatic Cancer Pathway Shows Distinct Immune Signatures
The discovery of alternative pathways to pancreatic ductal adenocarcinoma could fundamentally alter early detection str…
Studies
US Measles Cases Surge as MMR Coverage Drops Below Herd Immunity Threshold
The collapse of herd immunity protection threatens to reverse two decades of measles elimination success, potentially e…
Studies
Deep Silicon Photon-Counting CT Shows 4.3% Iodine Measurement Accuracy
Medical imaging's shift toward precision diagnostics gains momentum with breakthrough detector technology that dramatic…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.