Studies
First Controlled Human PK Study Maps Kratom's Opioid-Like Dose Response
For millions of adults using kratom as a self-managed alternative for pain, opioid withdrawal, or mood — with…
Longevity
Centenarian Offspring Gain Years of Disease-Free Life Across Three Cohorts
Most longevity research focuses on the centenarians themselves, but the more actionable question may be what happens…
Longevity
Ectopic ERBB4 in Excitatory Neurons May Drive Core Alzheimer's Pathology
For decades, Alzheimer's research has centered on amyloid plaques and tau tangles as the primary drivers of…
Studies
Brown Fat Hormone Nrg4 Cuts Atherosclerotic Plaques via Liver Enzyme Cascade
The discovery that fat tissue can function as an endocrine organ has quietly reshaped cardiovascular medicine — and a…
Studies
Oral FGFR Inhibitor Boosts Height Velocity 1.74 cm/Year in Achondroplasia Trial
For the estimated 250,000 people worldwide living with achondroplasia, the most common form of short-limbed dwarfism…
Fitness
Resistance Training Shifts Hunger Toward Ghrelin-Driven Episodic Patterns, Differently by Sex
Understanding why resistance training often fails to produce expected fat loss has puzzled researchers and…
Wellbeing
Psychedelics and Neuroplasticity Agents Reshape Depression Treatment Landscape
A convergence of mechanisms — from serotonin receptor agonism to rapid synaptic remodeling — is quietly redefining…
PREPRINTStudies
835-CpG Methylation Score Tracks Birthweight Independently in Preterm Twins
A cord blood methylation profile score (MPSBW) built from 835 CpGs previously linked to birthweight in the general…
PREPRINTStudies
8 Shared Genetic Loci Link Low Systemic Iron to Endometriosis Risk
Genetic analysis of large-scale GWAS data identifies 8 genome-wide significant shared loci between endometriosis and…
PREPRINTStudies
Flu and COVID Vaccine Uptake Linked 14-Fold in UK Adults Over 65
Among UK adults aged 65 and older enrolled in the FluSurvey participatory surveillance system across two consecutive…
PREPRINTStudies
Crowded Households Drive 69% Higher COVID-Like Outbreak Peaks in Farmworkers
A household-structured SIR transmission model reveals that agricultural workers face peak disease prevalence 1.41–1.69…
PREPRINTNutrition
Pro-Inflammatory Diet Raises Women's Metabolic Syndrome Risk 56% — Men Unaffected
Pooled analysis of 56,475 adults across the US, South Korea, and Mexico reveals a striking female-specific association…
Studies
GLP-1 Prescriptions for Young Children Rose 310-Fold Over Seven Years
The rapid expansion of GLP-1 receptor agonist use into elementary-school-aged children represents one of the more…
Studies
GLP-1 Agonists Clear Psoriasis Plaques While Slashing Metabolic Risk Simultaneously
Tirzepatide combination therapy in psoriasis patients delivered enhanced skin clearance, substantial weight loss, and…
Studies
Retatrutide Cuts Body Weight 22% in Non-Diabetic Obesity: GLP-1 Rankings Revealed
Across 58 randomized controlled trials enrolling 24,214 non-diabetic adults with overweight or obesity, retatrutide…
Longevity
Kidney Aging Maps p16-Driven Macrophage Niches Resisting Senolytic Clearance
In aging mouse kidneys, senescent tubular cells cluster with macrophages in anatomically discrete cortical zones…
Longevity
Fish Egg Peptides Extend C. elegans Lifespan 33% via Lipid Remodeling
At just 0.15 mg/mL, egg-derived peptides (EPs) from American shad (Alosa sapidissima) extended Caenorhabditis elegans…
Studies
FAPI PET/MRI Detects Deep Endometriosis Lesions Missed by Standard Imaging
For the millions of women living with endometriosis — often undiagnosed for years — the accuracy of initial imaging…
Wellbeing
Hippocampal Molecular Map Reveals Stalled Neurogenesis at Core of Depression
Understanding why antidepressants work for some people but fail others has been a persistent clinical puzzle — and new…
Studies
Microplastics Found in Tumor Tissues at Higher Concentrations Than Healthy Cells
The question of whether the plastic particles now saturating our food, water, and air are quietly reshaping cancer…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.