Studies
NEJM Editorial on Phase 1 Base-Editing Therapy for Non-Statin LDL Reduction
Cardiovascular disease remains the leading cause of death globally, and LDL cholesterol management sits at the center…
Studies
GLP-1 Weight-Loss Drugs Linked to Emerging Eating Disorder Risk Signals
As GLP-1 receptor agonists become among the most prescribed medications in history, a critical question is emerging…
Studies
Wogonin-Primed Exosomes in Smart Hydrogel Double Retention in Arthritic Joints
For the roughly 500 million people globally living with osteoarthritis, the absence of disease-modifying therapies—not…
Studies
PRAME-Targeted T-Cell Therapy Shows Early Promise in Pediatric Kidney Cancer
When a child's cancer resists standard treatment, the options narrow rapidly — and for pediatric nephroblastoma (Wilms…
Studies
PSA Kinetics in First Cycle Predict Adaptive Therapy Survival in Prostate Cancer
Personalized cancer treatment has long been constrained by a fundamental problem: clinicians cannot reliably predict…
Studies
mRNA Flu Vaccine Phase III Trial Reveals Efficacy and Safety Profile
The pivot from annual egg-based influenza vaccines to mRNA platforms could fundamentally change how quickly and…
Studies
Triple Reuptake Inhibitor Centanafadine Shows Pooled Efficacy Across ADHD Trials
For the millions of adults and children managing ADHD with medications that carry cardiovascular risks, abuse…
Studies
Portable MiniDock Device Advances Rapid Field Tuberculosis Diagnosis
Tuberculosis remains one of the leading infectious disease killers globally, claiming over a million lives annually…
Studies
NEJM Reviews Which Quit-Smoking Tools Actually Work in Underserved Populations
Tobacco use remains the single largest preventable cause of premature death globally, yet the vast majority of the…
Longevity
Cheek-Swab Epigenetic Clocks Track Health But Miss Socioeconomic Signals
For population-scale longevity research, the difference between a blood draw and a cheek swab is not merely procedural…
Studies
Gene Editing in Mouse Model Explores Therapeutic Path for Peroxisomal Disorders
For patients born with peroxisomal biogenesis disorders — a group of devastating inherited conditions that rob infants…
Longevity
Senescent Fibroblasts Drive Pulmonary Fibrosis Through Self-Reinforcing Cellular Loops
Idiopathic pulmonary fibrosis kills most patients within three to five years of diagnosis, yet the cellular machinery…
Studies
Phase 3 Trial: Soticlestat Misses Primary Endpoint in Dravet Syndrome Children
For families managing Dravet syndrome — one of the most treatment-resistant childhood epilepsies — every incremental…
Studies
CGM Linked to Lower HbA1c and Mortality Risk in Type 2 Diabetes, Yet Equity Gaps Persist
Continuous glucose monitoring has long been associated with tighter control in Type 1 diabetes, but its value across…
Studies
Fertility Preservation Access for Young Cancer Patients Reveals Stark Disparities
For young women diagnosed with cancer, the chance to preserve future fertility can be as consequential as the…
Studies
Cefazolin Matches Antistaphylococcal Penicillins in S. aureus Bloodstream Infections
Bloodstream infections caused by Staphylococcus aureus carry a mortality rate that rivals many cancers, yet a…
PREPRINTNutrition
8 Proteins Map Healthy Plant-Based Diets to Lower Cancer and CVD Risk
Analyzing 7,285 circulating protein aptamers in 4,372 EPIC cohort participants, researchers identified specific…
PREPRINTLongevity
AI Model Reads Coronary Angiograms With 0.94 AUROC, Rivals Expert Cardiologists
Trained on 135,475 coronary angiography examinations comprising 812,850 multi-view videos from two Shanghai hospitals…
PREPRINTLongevity
AF Linked to Brain Changes Independently of Stroke: Large UK Biobank MRI Study with Mendelian Randomization Support
Across 502,099 UK Biobank participants, atrial fibrillation (AF) independently associated with reduced global grey…
PREPRINTStudies
cFAS + Frailty Index Predicts Limb Loss Risk 4.5× After Vascular Surgery
Among 657 patients undergoing elective vascular surgery over a decade, high circulating fatty acid synthase (cFAS)…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.