Omega-3 Under 2000mg Daily Reduces Inflammation in Dialysis Patients

Natural triglyceride omega-3 supplements at doses below 2000mg daily reduced C-reactive protein levels in hemodialysis…

Antibiotics Reduce Lesion Volumes and Neuroinflammation in Male Mice After Traumatic Brain Injury via Gut Microbiome Remodeling

Antibiotic treatment following controlled brain injuries in male mice produced smaller lesion volumes, reduced cell dea…

Community Workshops Maintain Cardiovascular Risk Stability Over 2 Years While Controls Decline

Community-based health education workshops in Cardona, Spain successfully prevented the natural deterioration of cardio…

Estradiol Boosts Vaccine Response via mTOR Pathway in Female Mice

Female mice generated significantly stronger antibody responses to influenza vaccination than males through estradiol-d…

Senolytic Therapy Shows Sex-Specific Effects on Aged Bladder Function

Dasatinib and quercetin combination therapy produced distinct effects in 25-month-old female versus male mouse bladders…

Five Distinct Phenotypes Identified for Uremic Toxin-Driven Vascular Calcification

Researchers have mapped vascular calcification in chronic kidney disease into five distinct phenotypes, each driven by…

New Compound MPOL_B_1 Extends Worm Lifespan 30% Via Folate Transport

Researchers identified MPOL_B_1, a novel geroprotector compound that extends C. elegans lifespan by up to 30% through v…

RNASEK Enzyme Extends Lifespan by Clearing Toxic Circular RNA Aggregates

Scientists identified ribonuclease κ (RNASEK) as a critical enzyme that degrades circular RNAs (circRNAs), which accumu…

High-Frequency Hearing Above 8kHz Predicts Speech Recognition Accuracy

Individuals with superior hearing sensitivity above 8 kHz demonstrate markedly enhanced ability to predict spoken words…

Research Framework Links Chronic Infections to Long-Term Disease Patterns

A new analytical framework proposes standardizing how researchers study the connections between infectious agents and c…

SKIP

PNAS Theoretical Framework Redefines Koinophilia to Address Social Isolation

A PNAS framework redefines koinophilia—the evolutionary preference for typical or average traits—as a mechanism for add…

Uneven Blood Flow Through Brain Capillaries Emerges as Critical Factor

Variation in how quickly blood moves through individual brain capillaries—termed capillary transit time heterogeneity—a…

3D Lab Models Reveal Hidden Drug Resistance in Breast Cancer

Three-dimensional laboratory models incorporating patient-derived tissues now replicate the complex cellular environmen…

Host-Derived Volatile Primes Context-Dependent Foraging in Parasitic Nematodes via Lysosome-Associated Neural Pathway

Parasitic nematodes employ sophisticated chemical detection systems to modify their foraging behavior through lysosome-…

Multimodal Prostate Cancer Protocol Achieves 61% Undetectable PSA Rates

The MetaCURE trial tested an intensive multimodal approach combining apalutamide-based hormone therapy, surgical resect…

Antihistamine Drug Restores Myelin Sheaths in Primate Brain Model

Clemastine fumarate, a common over-the-counter antihistamine, successfully triggered myelin repair in nonhuman primates…

PARP Inhibitor Plus Antiangiogenic Drug Extends Survival in BRCA Breast Cancer

The FABULOUS trial demonstrates that combining fuzuloparib (a PARP inhibitor) with apatinib (an angiogenesis inhibitor)…

Long Non-Coding RNA RMRP Controls Mitochondrial Function Through Helicase Partners

Long non-coding RNA RMRP undergoes magnesium-dependent structural changes that enable specific binding to DEAD-box heli…

Malaria Parasite Enzyme Repurposed as Nanoparticle Delivers Complete Protection

Scientists engineered PLP synthase, an enzyme from malaria parasites, into stable nanoparticles displaying key parasite…