Longevity
Alamandine Reverses Age-Related Gut Leakiness and Bone Marrow Inflammation in Mice
Alamandine (Ala), a lesser-known renin-angiotensin system heptapeptide acting via the MrgD receptor, reverses multiple…
Longevity
Gut Bacterium Intestinimonas Linked to Pro-Inflammatory Brain T-Cell Shifts in Accelerated Aging
In SAMP8 accelerated-aging mice versus senescence-resistant SAMR1 controls, gut microbial diversity diverged…
Longevity
Healthspan Lags Lifespan by 2x at Age 60, Exposing Policy Gap
Applying remaining life expectancy as the threshold for 'old age' rather than fixed chronological cutoffs, this…
Longevity
Five Environmental Stressors Drive Cardiovascular Risk Below Regulatory Safety Thresholds
Cardiovascular disease guidelines have long focused on cholesterol, blood pressure, and lifestyle — but a sweeping new…
Studies
Spatial Multi-Omics Decodes Pre-Metastatic Niche Before Cancer Spreads
One of oncology's most frustrating realities is that metastasis — responsible for the vast majority of cancer deaths…
Studies
Global TB Burden Mapped Across 204 Countries: MDR-TB Progress Stalls
Tuberculosis remains one of the most consequential infectious disease crises in modern public health, and the prospect…
Supplements
Coumarin Compound Scoparone Targets miRNA-AMPK Pathway to Reverse Fatty Liver
Fatty liver disease has quietly become one of the most prevalent metabolic disorders worldwide, yet effective…
Studies
Flawed Unreviewed Vaccine Analysis Spread Misinformation Through Political Channels
When methodologically compromised research bypasses peer review and enters political hearings and documentary films…
Studies
Prenatal DEHP Exposure Shapes Autism and ADHD Risk via Cord Blood Epigenetics
Plastic is everywhere in modern life, but its chemical fingerprints may be written into children's DNA before birth…
Studies
Neutrophil Extracellular Traps Emerge as Liver Disease Therapeutic Target
Chronic and acute liver diseases remain among the most undertreated conditions in modern medicine, partly because the…
Studies
Liquid Crystal Monomers Identified as Novel PFAS Contamination Source
The story of environmental fluorine contamination keeps expanding, and that expansion matters for anyone tracking…
Studies
Fatal Immune Checkpoint Inhibitor Signals Demand Stricter Pharmacovigilance Methods
Fatal adverse events linked to cancer immunotherapy represent one of oncology's most pressing safety challenges, and…
Studies
Ribosome Palindrome Hypothesis Challenges Core Assumptions in Molecular Evolutionary Inference
Molecular biology's most fundamental machinery — the ribosome — has long been treated as a reliable phylogenetic clock…
Studies
Single-Dose Compound Clears Chagas Parasite in Mice via Selective Enzyme Inhibition
For the roughly 6–7 million people living with Chagas disease — most of whom will never complete the months-long…
Studies
Formin-1 Protein Mutations Linked to Hereditary Hearing Loss in Humans
Hereditary hearing loss affects roughly 1 in 500 newborns and has hundreds of known genetic causes — yet a significant…
Wellbeing
Facial Palsy Data Confirms Motor Simulation Role in Reading Emotional Expressions
Understanding how the brain decodes another person's emotional expression has practical stakes far beyond academic…
Studies
NEJM Trial Compares Antibiotic Duration Outcomes in Orthopedic Infections
Antibiotic stewardship — the push to use the shortest effective course of antibiotics — is one of the most…
Wellbeing
NEJM Case Reveals Overlapping Cognitive, Mood, and Wasting Triad in Older Woman
When three seemingly distinct symptoms converge in a single patient — cognitive decline, loss of pleasure, and visible…
Studies
Phase III Trial Establishes Blinatumomab as First-Line ALL Therapy
Acute lymphoblastic leukemia has long demanded grueling multi-agent chemotherapy regimens that exact severe toxicity…
Studies
NEJM Editorial Reassesses Sodium Bicarbonate Role in Critical Metabolic Acidosis
For decades, the use of sodium bicarbonate in critically ill patients with severe metabolic acidosis has occupied a…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.