Studies
Sweepstakes and Social Media Ad Tactics Distort Teen Nicotine Risk Perceptions
Understanding which advertising features systematically distort how young people perceive nicotine risk is now more…
Studies
HLA Loss After Stem Cell Transplant Varies Fivefold by Donor Type
For the roughly half of blood cancer patients who relapse after stem cell transplantation, understanding why the…
Studies
ALK Inhibitor Ceritinib Triggers Heart Damage via AKT-Autophagy-Mitochondrial Cascade
For cancer patients receiving targeted therapies, cardiovascular side effects can be as threatening as the disease…
Studies
Gut-Brain Peptide Network Mapped: Five Key Hormones Drive Appetite Architecture
Understanding why obesity is so difficult to reverse pharmacologically requires grasping the full architecture of…
Studies
CYBA Gene Suppression Blocks Pancreatic Cancer Liver Spread via AKT/MLC2 Signaling
Pancreatic cancer's lethality is largely driven by its tendency to spread to the liver before diagnosis, and few…
Longevity
Meta-Analysis Tests 16 Epigenetic Clocks Against 51 Longevity Interventions
The promise of epigenetic clocks has always been tantalizing: a molecular readout of how fast you're actually aging…
Studies
FOBT Colorectal Screening Cuts CRC Mortality More Than Raw Data Suggest
Colorectal cancer screening statistics routinely understate the true benefit of fecal occult blood testing — a…
Wellbeing
Largest Human Hippocampal Atlas Links Disrupted Neurogenesis to Depression Mechanisms
Depression research has long been hampered by a fundamental gap: the molecular machinery inside the living human…
Longevity
Deep Learning Reveals Nuclear Enlargement as Quantifiable Skeletal Muscle Aging Marker
Identifying reliable tissue-level markers of biological aging has long been a bottleneck for both clinical assessment…
Longevity
DNA Methylation Clocks Fail Key Surrogate Endpoint Validation Tests
For anyone banking on epigenetic clocks to guide longevity interventions, this investigation lands as a serious…
Wellbeing
NHS Psilocybin Trial Shows Feasibility for Treatment-Resistant Depression
For the millions living with depression that fails to respond to conventional antidepressants, the question is no…
Studies
Phase 3 Trial: Perioperative Apalutamide Cuts Prostate Cancer Residual Disease Tenfold
For the roughly half of high-risk localized prostate cancer patients who relapse within five years of surgery…
PREPRINTStudies
New Mortality Algorithm NeMMo Outperforms EuroMOMO in Detecting Pandemic Death Spikes
Analyzing weekly all-cause mortality data from 31 European countries (2015 onward, COVID-19 period excluded from…
PREPRINTStudies
Four MDR-TB Strains Drive 46% of Argentina's New Cases Over Decade
Genotyping of 1,189 multidrug-resistant Mycobacterium tuberculosis isolates collected across Argentina from 2013–2022…
PREPRINTLongevity
DunedinPACE Age Norms Derived from 37,855 Individuals Across 11 Cohorts
A meta-analysis of 11 cohorts encompassing 37,855 individuals aged 17–99 established the first population-based age…
PREPRINTStudies
1-in-3 Indian Children Have NAFLD; Obese Youth Hit 60% Prevalence
Pooling data from 11 Indian studies covering 3,512 children and adolescents under 18, this meta-analysis estimates an…
PREPRINTLongevity
Community-Level Urbanization and Wealth Concentration Linked to Higher Hypertension Odds Among Overweight Ethiopian Adults
Among 3,842 overweight and obese Ethiopian adults drawn from 612 clusters in the nationally representative 2024–25…
Supplements
GLP-1 Drugs Linked to 57% Lower Papilledema Risk in Intracranial Hypertension Patients
Across eight studies enrolling 13,243 patients, GLP-1 receptor agonists (GLP-1 RAs) produced striking reductions in…
Longevity
Evolved Gut Bacteria Extend Lifespan via Acetate in Drosophila Model
Applying directed evolution to the Drosophila gut microbiome outside the host generated a paraquat-resistant (PQR)…
Longevity
17α-Estradiol Cuts Fat in APOE4 Females But Misses Brain Targets
Treating 12-month-old female mice carrying the APOE4 Alzheimer's risk allele with 14.4ppm 17α-estradiol (17αE2) for…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.