Studies
AI-Designed Mini-Proteins Block Complement C9 With 700pM Affinity
Blocking the final step of complement activation could transform treatment for dozens of autoimmune and inflammatory…
Studies
Armed Conflicts Show Weak Links to HIV Outcomes Across 22 Nations
The assumption that armed conflict inevitably devastates HIV care appears less straightforward than previously…
Studies
Plasma Lipid Patterns Mirror Prostate Cancer Metabolic Changes, Predict Treatment Response
Blood-based metabolic fingerprinting could revolutionize how oncologists monitor advanced prostate cancer treatment…
PREPRINTLongevity
Analysis Maps U.S. POINTER Cognitive Gains to Small 0.06-0.31% Reductions in Predicted Dementia Progression Risk
External validation analysis found that the modest cognitive improvements from U.S. POINTER's structured lifestyle…
PREPRINTStudies
ADRB1, CACNB2 Gene Variants Reduce Pregnancy Hypertension Risk 7%
Genetic variants mimicking beta-blocker and calcium-channel blocker drug targets reduced preeclampsia risk by 7% per 1…
PREPRINTStudies
Genetic Evidence Suggests Lp(a)-Lowering Unlikely to Harm Pregnancy Outcomes
Using genetic variants that naturally lower lipoprotein(a) levels as proxies for future Lp(a)-targeting drugs…
PREPRINTStudies
PAD Associated with Higher Odds of Bleeding, Vascular Complications in AF Ablation
Analysis of 22,166 atrial fibrillation catheter ablations revealed that patients with peripheral artery disease (PAD)…
PREPRINTStudies
AI-ECG Models Show High Test-Retest Reliability (CCC 0.90) for Structural Heart Disease Detection
AI-enhanced electrocardiography models achieved concordance correlation coefficients of 0.90 for both signal- and…
Studies
Social Science Studies Show 66% Analysis Variability Despite Identical Datasets
The foundation of evidence-based health recommendations may be shakier than assumed. When different analysts examine…
Studies
Atopic Dermatitis Patients Show Over 2-Fold Higher Retinal Detachment Risk
Adults managing chronic skin inflammation may need enhanced eye care monitoring, as new evidence reveals unexpected…
Studies
Lean MASLD Patients Face Double Liver-Related Death Risk
The assumption that lean individuals with fatty liver disease face better outcomes than their overweight counterparts…
Studies
Breast Cancer Incidence and Mortality Projected to Rise Substantially by 2050 Across 204 Countries
The trajectory of breast cancer worldwide reveals an alarming acceleration that will fundamentally reshape healthcare…
Studies
Intestinal Energy Absorption Associated with Bariatric Surgery Weight Loss Outcomes
Understanding why some patients thrive after bariatric surgery while others struggle could transform how physicians…
Studies
Antibody-Drug Conjugate Halves Recurrence Risk in High-Risk Breast Cancer
Women facing the highest breast cancer recurrence rates now have compelling evidence for a treatment shift that could…
Fitness
Performance Drug Classes Show Limited Athletic Benefits Despite Cardiovascular Risks
The prospect of medically supervised performance enhancement in competitive athletics reveals a troubling disconnect…
Wellbeing
Brain Stimulation Reduces Bladder Problems, Costs in Stroke Survivors
Bladder dysfunction affects up to 80% of stroke survivors, creating both physical discomfort and significant…
Wellbeing
Team-Based Integrative Care Reduces Chronic Pain Interference More Than Standard Treatment
Chronic pain affects millions of Americans, yet traditional medical approaches often fall short of meaningful relief…
Wellbeing
Neuroinflammation Emerges as Key Driver Connecting Amyloid and Cognitive Decline
Understanding how brain inflammation accelerates cognitive decline could reshape prevention strategies for the 55…
Wellbeing
Vagus Nerve Stimulation Reduces Motor Errors in Complex Movement Tasks
Motor control deteriorates when we attempt complex movements or rapidly switch between different action types, leading…
Studies
Single mRNA Vaccine Platform Achieves Cross-Protection Against Three Deadly Ebolaviruses
The persistent threat of Ebola outbreaks has exposed a critical gap in pandemic preparedness: existing vaccines target…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.