Studies
AAV Gene Therapy Shows Major LDL-C Reduction in Phase 1 Homozygous FH Trial
For individuals born with defective cholesterol-clearing genes, this breakthrough could transform a lifelong battle…
Studies
Novel RAS Inhibitor Shows 35% Response Rate in Pancreatic Cancer
Pancreatic cancer remains among medicine's most formidable challenges, with five-year survival rates below 12% and…
Wellbeing
Tactile Robot Companion Improves Emotion Regulation and Reduces Depressive Symptoms in LGBTQ+ Youth
Mental health interventions for vulnerable youth populations may soon incorporate an unexpected ally: therapeutic…
Studies
Global Foodborne Illness Deaths Hit 1.5 Million Annually, WHO Data Shows
The scope of foodborne illness as a global health threat has crystallized with unprecedented precision, revealing that…
Wellbeing
Study Links Prenatal PFAS Exposure to Sex- and Compound-Specific Differences in Pubertal Timing in Spanish INMA Cohort
The disruption of normal pubertal timing may signal broader reproductive health challenges for an entire generation…
Studies
Multi-Cancer Blood Test Fails to Reduce Advanced Cancer Cases in UK Trial
The promise of catching dozens of cancers with a single blood draw has hit a significant roadblock, potentially…
Wellbeing
AI Documentation Tools Cut Clinical Note Time by 2 Minutes Daily
Electronic health record documentation consumes nearly half of physicians' workdays, contributing to widespread…
Studies
MHC-I Loss Shows Opposite Effects on Liver vs Colon Tumors
The immune system's response to cancer cells missing a key identification marker varies dramatically by tumor type…
Studies
A*STAR Develops Microgel-Integrated Microneedle Patches for Improved Protein Loading, Stability, and Transdermal Delivery in Preclinical Tests
The promise of painless, self-administered medicine delivery has moved significantly closer to reality with…
PREPRINTLongevity
Immune Cell Sex Differences Don't Explain Male Mortality Gap
Analysis of 8,822 older adults revealed substantial sex differences in 39 of 48 immune cell biomarkers, with…
PREPRINTStudies
AI Analysis Identifies 19 Age-Specific OSA Comorbidity Patterns in 36,426 Patients
Advanced topic modeling of electronic health records from 36,426 obstructive sleep apnea patients revealed 19 distinct…
PREPRINTLongevity
METS-IR Score Predicts 49% Higher Arrhythmia Risk Over 22 Years
The METS-IR metabolic index demonstrates strong predictive power for cardiac arrhythmias in a comprehensive 22-year…
PREPRINTWellbeing
Maternal Psychiatric Disorders Associated with 19% Higher Offspring Heart Disease Risk
A massive Swedish registry analysis of 4.17 million births found that maternal psychiatric disorders diagnosed before…
PREPRINTLongevity
AI Analysis Links Metolazone, Varenicline to Protective Associations Against Dementia in Million-Veteran Study
Analysis of over one million Veterans' health records using advanced artificial intelligence identified metolazone (a…
Wellbeing
Reflective Rumination Enhances Mood Benefits from Positive Social Media Experiences Among Hispanic Adults
How we mentally process social media interactions may determine whether platforms harm or help our psychological…
Studies
Lipoprotein(a) Elevates Heart Disease Risk Even With Zero Calcium Score
Heart disease prevention may need fundamental recalibration as emerging evidence challenges the reliability of…
Longevity
Progranulin Protein Deficiency Accelerates Vascular Aging Through Cellular Senescence Pathways
Progranulin deficiency in mice triggers premature vascular senescence, causing endothelial dysfunction, enhanced…
Wellbeing
Sex Chromosomes Influence Brain Stress Responses in Mice, Often Independent of Gonad Type
Understanding why women experience depression at twice the rate of men could reshape how we approach mental health…
Studies
EBV Can Cause Lymphomas in Human Cell Mouse Model Without Essential Viral Protein EBNA2
The discovery that Epstein-Barr virus can drive cancer formation without a protein long considered essential…
Studies
AI Maps Complex Protein Mutation Patterns for Enhanced Engineering
Protein engineering has long been hampered by the astronomical complexity of predicting how multiple mutations…
Browse Topics
Longevity & Anti-Aging Research Nutrition & Diet Science Exercise & Fitness Science Wellbeing & Integrative Health Medical Studies & Clinical Trials Supplements & Nutraceuticals✉️ Stay Updated
Get daily health research summaries delivered to your inbox.
Health & Longevity Topics
Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.