Studies
Multi-Cause Death Certificate Analysis Reveals Hidden Mortality Burden in US Data
How Americans actually die is more complex than official death statistics suggest — and that gap between recorded data…
Studies
Chromosomal Instability Drives Tumor Growth Via Neighboring Healthy Cells
Cancer treatment strategies built on destabilizing tumor chromosomes may be more complicated than previously assumed…
Studies
Radiotheranostic Cancer Therapy Shows Promise But Cost-Effectiveness Evidence Remains Thin
As precision oncology increasingly captures headlines, a quieter revolution in cancer treatment is raising an urgent…
Studies
CTCs Track Response to TROP2/HER2 ADCs in Metastatic Breast Cancer but Target Expression Does Not Predict Outcomes
For the millions of women with metastatic breast cancer, knowing whether a targeted therapy is actually reaching and…
Studies
Meningitis Kills 259,000 Annually; Pneumococcal Pathogen Leads 17-Cause Analysis
For parents of young children, global health advocates, and anyone tracking infectious disease risk, this landmark…
Studies
Stronger Innate Immune Responsiveness Predicts Worse Flu Symptoms in Challenge Study
Most people assume a more reactive immune system is unconditionally protective — this research challenges that…
Studies
34-CircRNA Blood Panel Outperforms pTau217 in Predicting Alzheimer's Onset
The window for intervening in Alzheimer's disease before irreversible neurodegeneration takes hold is narrow — and…
Studies
51-Trial Meta-Analysis Finds Blood Pressure Drug Benefits Don't Compound Over Time
For decades, the standard clinical assumption has been that staying on blood pressure medication longer yields…
Studies
Prior H1N1 Exposure Builds Partial Cross-Immunity Against H5N1 Neuraminidase
If H5N1 bird flu ever achieves sustained human transmission, the pandemic toll may not fall equally across all age…
Studies
Alcohol Industry Opposed 99% of Pregnancy Label Proposals in Australia-NZ
When public health policy collides with commercial interests, the lobbying record tells a revealing story…
Wellbeing
Gendered Digital Environments Linked to Distinct Mental Health Risks in Young Males
The mental health conversation around screen time has long centered on girls and young women — but a growing body of…
PREPRINTStudies
ML Screens Undiagnosed Hypertension With Just 8 Non-Invasive Variables—But AUC Barely Clears 0.61
Among 5,237 NHANES 2017–2018 participants, 20.5% (n=1,072) met criteria for probable undiagnosed hypertension (mean BP…
PREPRINTStudies
POAF After Bypass Surgery Extends Stay 30% But Doesn't Drive 90-Day Readmissions
Among 4,684 adults undergoing isolated coronary artery bypass grafting (CABG) in Florida between 2021 and 2024…
PREPRINTLongevity
5-Phenogroup Model Reveals Lean-IR Patients Face 1.86x MI/Stroke Risk
Latent class analysis applied to 1,034 participants (RESET cohort) using 14 cardiometabolic variables—six conventional…
PREPRINTLongevity
Custom 47,027-SNP Array Detects 84% of FH Variants Across Multi-Ethnic NZ Cohort
A custom Illumina Global Screening Array — branded Holo-Q Omniscan Waka Te Ira — was engineered with 43,437 added SNPs…
PREPRINTStudies
Whole Exome Sequencing Finds 9% of MVP Patients Carry High-Risk Arrhythmia Genes
In 203 consecutive mitral valve prolapse (MVP) patients without other arrhythmic substrates, whole exome sequencing…
Studies
Telehealth Stepped Alcohol Treatment Cuts Drinking in Liver Disease Patients
For the millions of people managing chronic liver disease while also struggling with alcohol use disorder, finding an…
Supplements
5 Polyphenols Target ADPKD Cyst Growth via 4 Simultaneous Pathways
Five plant-derived polyphenols — resveratrol, curcumin, naringenin, quercetin, and EGCG — demonstrate preclinical…
Nutrition
Polyphenols Raise LDL Numbers Yet Cut Oxidized LDL 65% in Equol Producers
A randomized, placebo-controlled crossover trial (PolyPAUSE, n=90 mildly hypercholesterolemic postmenopausal women)…
Supplements
Resveratrol Fights Obesity via p38-ATF3-GDF15 Brain Signaling Cascade
Resveratrol dose-dependently upregulates GDF15 mRNA, protein expression, and secretion in both murine embryonic…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.