Studies
KRAS Molecular Glues Expand From Single Mutations to Pan-RAS Cancer Targeting
For decades, KRAS was considered undruggable — a death sentence for patients whose tumors carried mutations in this…
Studies
E3 Ubiquitin Ligase RNF10 Loss Triggers Cardiac Mitophagy Failure and Hypertrophy
Cardiac hypertrophy — the pathological thickening of heart muscle — remains one of the leading precursors to heart…
Studies
Plant Terpenoid Costunolide Targets USP15 to Quell Retinal Autoimmune Inflammation
Autoimmune uveitis silently destroys vision in millions of people worldwide, yet every approved therapy works by…
Studies
Unique Enzymes Driving C. difficile Flagellar Sugar Assembly Identified
Understanding how dangerous gut pathogens build their molecular armor could eventually open new therapeutic avenues…
Studies
Brain Tumor Growth Hijacks Cell Competition to Overcome Tissue Resistance
Understanding how nascent tumors escape the physical constraints of healthy tissue is one of cancer biology's most…
Wellbeing
Procrastination and Impulsivity Share Measurable Neurogenetic Architecture in Brain
For anyone who has ever wondered why they delay important tasks despite knowing better, a convergence of genetics and…
Wellbeing
Long-Lived Synaptic Proteins Show Sex-Dependent Turnover Rates in Brain
How the brain maintains stable memories and functional synapses over decades is one of neuroscience's most compelling…
Longevity
Brain Blood Flow Regulation Traced to Endothelial Arf6-PIP2-Kir2.1 Molecular Cascade
Maintaining sharp cognitive function across decades depends critically on the brain's ability to rapidly route blood…
Studies
Vestibular Ganglion Neurons Mapped Into Distinct Spatial Cell Types
Balance disorders and unexplained dizziness affect tens of millions of adults, yet the cellular architecture…
Studies
Magnetic Microrobots Disrupt Biofilm and Restore Immune Function Sequentially
Chronic wound infections and implant-associated biofilms represent one of medicine's most stubborn problems — not…
Studies
GCN2 Kinase Deficiency Drives IL-6-Mediated Pulmonary Hypertension in Mice
Pulmonary hypertension remains one of the most underdiagnosed and poorly understood cardiovascular conditions, with…
Studies
Stress Granules Actively Gate Cancer Cell Communication During Oxidative Stress
How cancer cells manage their molecular communications under duress has long been a blind spot in tumor biology — and…
Studies
Atomic-Level Maps of Antibodies Blocking Two Dangerous Brain-Targeting Viruses
For the millions of people living with HIV, undergoing organ transplantation, or receiving immunosuppressive therapies…
Studies
Mechanical Force Patterns Spatially Direct New Blood Vessel Growth in Tissue
Vascular biology has long assumed that chemical gradients—growth factors like VEGF diffusing through tissue—are the…
Nutrition
Online Food Delivery Widens China's Obesity Gap Along Socioeconomic Lines
The rapid digitization of food access may be quietly restructuring who gets sick and who stays healthy — and new…
Studies
Histone Chaperone HIRA Links Epigenomic Control to Fat Tissue Metabolism
Understanding why fat tissue malfunctions in obesity has long focused on hormones and calories, but the molecular…
Studies
One-Third of US Women Uncertain About Perimenopause Stage, Survey Finds
Perimenopause is one of the most consequential yet least clinically defined transitions in a woman's reproductive life…
Studies
Single-Cell Multi-Omics Reveals Hidden Clonal Drivers of Myeloma Drug Resistance
Drug resistance remains the central unsolved problem in multiple myeloma, a blood cancer where most patients…
Studies
Phase 1 Trial Shows SOD1-Targeting siRNA Conjugate Safe in ALS Patients
Amyotrophic lateral sclerosis remains one of the most devastating neurodegenerative diseases, and the SOD1-mutant…
Studies
Enteric Disease Mortality Down ~66% Since 1990, With Ongoing Burden in High-Risk Regions
Diarrhoeal and enteric infections remain a leading killer of young children globally, yet the pace of improvement has…
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Browse our synthesized research summaries by topic. We cover the latest findings from journals like Nature Medicine, The Lancet, Cell Metabolism, and 100+ other peer-reviewed sources.