Analysis of 3,432 patients across 57,227 primary care visits revealed that 72% maintained adequate statin adherence (≥80% proportion of days covered) during their first two years of treatment. Mean adherence reached 91.6%, with older patients showing 70% higher odds of compliance compared to younger counterparts. Multiple medication use and higher socioeconomic status each increased adherence likelihood by 80%, while switching between different statin types reduced compliance by 40%. This real-world evidence challenges assumptions about medication burden, suggesting that patients managing multiple conditions may actually demonstrate better adherence patterns, possibly due to increased healthcare engagement or recognition of cardiovascular risk. The findings have significant implications for preventive cardiology, as poor statin adherence directly correlates with increased cardiovascular events and healthcare costs. However, this observational study cannot establish causality, and the dataset's geographic and demographic scope may limit generalizability. As a preprint awaiting peer review, these results require validation before informing clinical guidelines. The research provides valuable baseline data for developing targeted interventions to improve medication adherence in primary care settings.